Harvard Biomarkers of Sleepiness Conference Agenda

Conference Agenda

SEPTEMBER 21, 2010TimeSpeaker
Registration8:00-8:30 am
Welcome8:30-8:35 amDr. Stuart Quan
Impact of Sleepiness on Public Health--
The Utility of a Biomarker
8:35-9:00 amDr. Charles Czeisler
Biomarkers and Heart Disease9:00-9:40 amDr. Michelle Albert
Biomarkers and Cancer9:40-10:20 amDr. Robin Farias-Eisner
Break10:20-10:35 am

Utility of Current Instruments to Measure
Sleepiness
10:35-11:15 am
Dr. Thomas Balkin
Electrophysiologic Markers of Sleepiness11:15-11:45 amDr. James Krueger
Lunch11:45 am-1:00 pm
Behavioral and Genetic Markers
of Sleepiness
1:00-1:45 pmDr. Namni Goel
Panel Discussion--
Current Status of Measuring Sleepiness
1:45-2:15 pmDrs. Czeisler, Goel,
Krueger, Balkin and
Mullington (Moderator)
Break2:15-2:30 pm
Changes in Gene Expression with Sleep2:30-3:30 pmDr. Paul Shaw
Potential of Proteomics as a Bioanalytic   
Technique for Quantifying Sleepiness
3:30-4:30 pmDr. Nirinjini Naidoo

SEPTEMBER 22, 2010TimeSpeaker
Association of Inflammatory Markers and
Sleepiness
8:00-9:00 amDr. Michelle Miller
Traffic and Work Safety: Nonlinear Transient
Analysis to Enhance a Posturographic
Sleepiness Tester
9:00-10:00 amDr. Edward Haeggstrom
Break10:00-10:15 am
Biochemical Regulation of Sleep and
Implications for a Biomarker
10:15-11:15 amDr. James Krueger
Genomic and Proteomic Approaches to
Biomarker Identification
11:15 am-12:15 pmDr. George Church
Panel Discussion--Can There Be a
Biomarker for Sleepiness?
12:15-12:45 pmDrs. Church, Krueger,
Miller, Haeggstrom,
Naidoo, Shaw, and Quan
(Moderator)


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Names and Credentials of the Speakers

A talented group of speakers were identified by the organizing committee and selected based on their expertise in biomarkers or genomic, proteomic, metabolic, behavioral or electrophysical associations with sleep loss or sleepiness.
  • Michelle Alpert, MD: Dr. Albert is an Assistant Professor of Medicine at Harvard Medical School and Brigham and Women's Hospital. She has expertise in the utility of biomarkers in the evaluation and treatment of heart disease. She will speak on “Biomarkers and Heart Disease”.
  • Thomas Balkin, PhD: Dr. Balkin is Chief, Department of Behavioral Biology, Walter Reed Army Institute of Research (WRAIR). He is an expert on the impact of sleep loss on human performance and alertness. He will speak on the “Utility of self-reported measures of sleepiness.
  • George Church, PhD: Dr. Church is Professor of Genetics, Harvard Medical School, Director of the Harvard/MIT DOE Genomes-to-Life Center, Director of the Harvard/MIT/Washington University NHGRI CEGS and Senioir Associate of the Broad Institute of Harvard & MIT. He is an internationally recognized expert in genomics and proteomics. He will speak on “Genomic and Proteomic Approaches to Biomarker Identification”.
  • Charles A. Czeisler, PhD, MD: Dr. Czeisler is the Baldino Professor of Sleep Medicine, Chief of the Division of Sleep Medicine at Brigham and Women’s Hospital and Director of the Division of Sleep Medicine at Harvard Medical School. He is an expert on circadian biology and the impact of shift work/extended work shifts on human performance. He will give the keynote lecture, “Impact of Sleepiness on Public Health--Utility of a Biomarker”.
  • Namni Goel, PhD: Dr. Goel is a Research Assistant Professor in Psychiatry in the School of Medicine, University of Pennsylvania. Her research investigates how physiological, behavioral and environmental fac-tors affect sleep, circadian rhythms and regulate mood. She will speak on "Behavioral and Genetic Markers of Sleepiness".
  • Edward Haeggström, PhD, MBA: Dr. Haeggström is Professor in Electronics and Measurement tech-niques, University of Helsinki and Visiting Professor, Harvard Medical School. He has broad interests in electronics, instrumentation and measurement method development for different applications in physics, medicine, and engineering. He will speak on Nonlinear Transient Analysis to Enhance a Posturographic Sleepiness Tester.
  • James F. Kruger, PhD: Dr. Kruger is Regents Professor of Veterinary & Comparative Anatomy, Pharmacology & Physiology at Washington State University. Dr. Kruger is a well recognized scholar in the neuropharmacologic regulation of sleep and wakefulness. He will make a presentation on “Biochemical Regulation of Sleep and Implication for a Biomarker”.
  • Nirinjini Naidoo, PhD: Dr. Naidoo is Research Assistant Professor in the Division of Sleep Medicine at the University of Pennsylvania School of Medicine. Dr. Naidoo is currently working in the area of proteomic markers of sleepiness and will speak on the “Potential of Proteomics as a Bioanalytic Technique for Quantifying Sleepiness”.
  • Michelle Miller, PhD: Dr. Miller is Associate Professor (Reader) in Biochemical Medicine at the University of Warwick Medical School in Coventry, United Kingdom. She is well versed on the association of inflammatory markers and sleepiness, and will speak on the “Association of Inflammatory Markers and Sleepiness”.
  • Paul J. Shaw, PhD: Dr. Shaw is Assistant Professor of Neurobiology, Washington University School of Medicine. His area of expertise is the genetic regulation of sleepiness. He will speak on “Changes in Gene Expression with Sleep”.
  • Robin Farias-Eisner, MD: Dr. Farias-Eisner is currently the Chief of Gynecology and Gynecologic Oncology in the Department of Obstetrics and Gynecology at UCLA, a Principal Investigator for the National Cancer Institute (NCI) - Gynecologic Oncology Group (GOG) and the Director of the Center for Biomarker Discovery and Research at UCLA that is dedicated to the prevention and early detection of women's cancers. He is an expert in the usefulness of biomarkers in cancer diagnosis and treatment. He will make a presentation on “Biomarkers and Cancer—Lessons for Sleep Research”.

Organizing Committee

  • Stuart F. Quan, MD (Conference Director): Dr. Quan is a Lecturer in Medicine at Brigham and Women’s Hospital, Harvard Medical School and Professor Emeritus of Medicine at the University of Arizona. He is the Editor of the Division’s Sleep and Health Education Program and the Editor-in-Chief of the Journal of Clinical Sleep Medicine. His research focuses on the epidemiology of sleep disorders with an emphasis on sleep disordered breathing.
  • Charles A. Czeisler, PhD, MD: Dr. Czeisler is Baldino Professor of Sleep Medicine and Director of Division of Sleep Medicine at Harvard Medical School and Brigham and Women’s Hospital. He is an internationally known circadian rhythm researcher, as well as an expert in the health consequences of shift work and sleep loss.
  • Janet M. Mullington, PhD: Dr. Mullington is Associate Professor of Neurology at Beth Israel Deaconess Medical Center, Harvard Medical School. She is Associate Director of the Beth Israel Deaconess Site of the Harvard Clinical and Translational Science Center. Her research interests include the role of inflammatory markers in sleep loss.
  • Thomas E. Scammell, MD: Dr. Scammell is Associate Professor of Neurology at Beth Israel Deaconess Medical Center, Harvard Medical School. His research focus is on the role of hypocretin in sleep and wakefulness.

This conference was made possible with the support of:

National Heart Lung and Blood Institute Grant #HL104874
Cephalon
Philips Healthcare

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