Faculty Profile

Jonathan Lipton, MD, PhD

Instructor in Neurology, Harvard Medical School
Instructor in Neurology, Sleep, Department of Neurology, Children's Hospital Boston

See publications

Inter-office Mail Address

Center for Life Science 13-060

Phone 781-216-2570

Society Memberships

American Academy of Neurology
American Academy of Sleep Medicine
Child Neurology Society
Society for Neuroscience

Research Unit(s)

Laboratory of Mustafa Sahin, MD, PhD, Department of Neurology, Children’s Hospital

Research Interests

Sleep disorders are extremely common in children with neurodevelopmental disorders such as autistic spectrum disorders (ASD) and tuberous sclerosis complex (TSC). I am investigating the molecular mechanisms that underlie these disorders in animal models. My goal is better understand fundamental mechanisms that link brain development and sleep. This will hopefully lead to rational therapeutic approaches for children with sleep disorders and ASDs.


Vicky Wu, BS 2008-2009


Mustafa Sahin, MD, PhD

Research Funding

Tuberous Sclerosis Alliance, American Academy of Neurology, William Randolph Hearst Foundation

Selected Publications

Original Articles

Lipton J, Megerian JT, Kothare SV, Cho YJ, Shanahan T, Chart H, Ferber R,
Adler-Golden L, Cohen LE, Czeisler CA, Pomeroy SL. Melatonin deficiency and
disrupted circadian rhythms in pediatric survivors of craniopharyngioma.
Neurology. 2009 Jul 28;73(4):323-5. [PMID: 19636054]

Lipton J, Rivkin MJ. 16p11.2-related paroxysmal kinesigenic dyskinesia and dopa-responsive parkinsonism in a child.
Neurology. 2009 Aug 11;73(6):479-80. [PMID: 19667324]

Lipton J, Joffe S, Ullrich NJ. CNS relapse of acute myelogenous leukemia masquerading as pseudotumor cerebri.
Pediatr Neurol. 2008 Nov;39(5):355-7. [PMID: 18940560]

Lipton J, Kleemann G, Ghosh R, Lints R, Emmons SW. Mate searching in Caenorhabditis elegans: a genetic model for sex drive in a simple invertebrate.
J Neurosci. 2004 Aug 25;24(34):7427-34. [PMID: 15329389]


Lipton J, Becker RE, Kothare SV. Insomnia of childhood. Curr Opin Pediatr.
2008 Dec;20(6):641-9. Review. [PMID: 19005332]

Lipton J, Rivkin, MJ. Kawasaki disease: cerebrovascular and neurologic complications.
In: Uncommon Causes of Stroke (editor LR Caplan). Cambridge, UK: Cambridge University
Press; 2008.

Lipton J, Cho Y, Megerian J, Shanahan T, Cohen L, Ferber R, Czeisler C, Kothare SV, Pomeroy SL. Disruption of Circadian Melatonin Secretion in Pediatric Craniopharyngioma Survivors with Hypersomnolence.
Sleep (Abstract). 2008.

Lipton J. Mating worms and the cystic kidney: Caenorhabditis elegans as a
model for renal disease.
Pediatr Nephrol. 2005 Nov;20(11):1531-6. Epub 2005 Jun 10. Review. [PMID: 15947985]

Emmons, S.W. and Lipton, J. The genetic basis of male mating behavior.
Journal of Neurobiology. 2003;54:93-110.

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