Faculty Profile

Stuart F. Quan, MD

Stuart F. Quan, MD
Gerald E. McGinnis Professor of Sleep Medicine, Harvard Medical School
Senior Physician, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital

Administrative Title(s)

Editor, Sleep and Health Education Program

Other Affiliation(s)

Professor Emeritus of Medicine, University of Arizona College of Medicine

See publications


Address

Clinical: Brigham and Women's Faulkner Hospital 1153 Centre Street Suite 4930, Boston, MA
Academic: 164 Longwood Ave. Boston, MA 02115

Phone 617-983-7420

Email Stuart_Quan@hms.harvard.edu

Society Memberships

American Academy of Sleep Medicine
Sleep Research Society
American Thoracic Society
American College of Chest Physicians

Research Interests

I am interested in the epidemiology of sleep disorders, particularly sleep disordered breathing. Current projects are the following: Sleep Heart Health Study (Observational cohort study to determine the cardiovascular consequences of sleep-disordered breathing; Role: Steering Committee Chair and PI of the University of Arizona site), Tucson Children’s Assessment of Sleep Apnea (TuCASA, Observational cohort study to determine the impact of sleep disordered breathing in children; Role: PI), and the Applied Positive Pressure Long-term Efficacy Study (APPLES, Randomized clinical trial to determine the neurocognitive consequences of sleep disordered breathing; Role: PI University of Arizona site).

Trainees

Terri Muchenau, 1981-1982
Judith Fahey, 1996-1997
Dana Epstein, RN, PhD 1994-1996
Derek Loewy, PhD 1996-1998
Tracy Kuo, 1997-2000
Derek Loewy, 1999-2000
Maria Martinez, MD 1999-2000
Abdul Hourani, MD 2000-2001
Arnel Bobadilla, MD 2001-2002
Shelagh Mulvaney, 2001-2002
James L. Goodwin, PhD 2000-2002
Carol M. Baldwin, RN, PhD 2002-2004
Yu-Ju Chen, 2003-2006
Graciela Silva, PhD 2005-2006
Claire Venker, 2005-2006
Qiuhong Zhao, 2005-2006
Parvathy Nair, M.D. 2009-2010
Mark Brown, M.D. 2007-2010
Oscar Furet, 2009-2010

Mentor(s)

Richard Schlobohm, M.D.
Richard J. Lemen, M.D.
Michael D. Lebowitz, Ph.D.

Research Funding

5R01HL062373-09     Quan (PI)     1/1/05-11/30/09
NIH, National Heart, Lung Blood Institute
NHLBI: Impact of Childhood Sleep Disordered Breathing
The primary objectives of this study are to determine the impact of sleep disordered breathing (SDB) identified in preadolescents on subsequent school and neurocognitive performance, to assess factors, which influence the natural history of SDB in children and to ascertain whether these elements differ between Caucasians and Hispanics.
Role: PI

1RC2HL101417-01    Quan (PI)     10/1/09-9/30/11
NHLBI: Phase II Trial of Sleep Apnea Treatment to Reduce Cardiovascular Morbidity
Subcontract from Case Western Reserve University
This is a clinical trial designed to determine whether CPAP and/or supplemental nocturnal oxygen reduce cardiovascular disease risk factors in patients with coronary artery disease and obstructive sleep apnea.
Role: Site PI

HL095748-01    Parthsarathy (PI)    8/1/09-7/30/14
NHLBI: Sleep Intervention during Acute Lung Injury
This is a clinical trial to determine the role of a alpha blocking agent in improving sleep in ICU patients with acute lung injury.
Role: Co-I

Department of Transportation    Quan (PI)    3/16/2010-3/15/2015
Sleep and Health Education Program: A Web-Based Sleep Disorders Screening Survey and Education Module on Sleep Health and Safety in the Railroad Industry
This is a contract to develop a web-based sleep disorders screening survey and educational module for train operators.
Role: PI and Overall Editor

Completed Research

American Sleep Medicine Foundation Quan (PI)        1/1/10-12/31/10
Developing and Testing an Online Sleep Education Presentation for College Psychology Students
This is a study to determine  whether online interactive material improves sleep knowledge in a cohort of students enrolled in an introductory college psychology class.
Role: PI

U01 HL068060    Quan (PI)    09/30/02-07/31/08
NIH, Subcontract from Stanford Tucson Field Center
Applied Positive Pressure Levels in Sleep Apnea (APPLES)
The goal of this grant is to determine the long-term effects of nasal CPAP on neurocognitive function in obstructive sleep apnea.
Role: Site PI

5U01HL053938-12     Quan (PI)    9/01/04-08/31/08
NIH, National Heart, Lung and Blood Institute                     
University of Arizona Clinical Site Steering Committee Chair           
Sleep Heart Health Study
This grant is a Multi-site epidemiologic study to determine the cardiovascular consequences of sleep disordered breathing.
Role: Site PI

Teaching

1980 Postgraduate Clinical Seminar Series- Diagnosis and Treatment of Pneumonia
Single Presentation, University of Arizona

1981 Emergency Care Update: New and Changing Patterns of Pneumonia, and Panel on “Chest Pain Single Presentation and Panel
Discussion, University of Arizona

1982 Asthma—What’s New”, Invited Faculty; Emergency Case Update - IV
Single Presentation, University of Arizona

1982 Postgraduate Clinical Seminar Series- Diagnosis of Sleep Apnea
Single Presentation, University of Arizona

1982 Postgraduate Clinical Seminar Series: Treatment of Acute Exacerbations and Indications for Ventilator Care in Chronic AOD
Single Presentation, University of Arizona

1983 High Frequency Ventilation, Arizona Chest Symposium
Single Presentation, University of Arizona

1985 Primary Care Update- Hypersomnolence and Sleep Apnea
Single Presentation, University of Arizona

1986 Ventilators—Basics in Management, Arizona Chest Symposium
Single Presentation, University of Arizona

1987-1988 Primary Care Update- Basic Pulmonary Function Testing in the Primary Care Office
Single Presentation, University of Arizona

1993 Sepsis and Septic Shock: Management Challenges for the 1990s
Program Chairman and Moderator, University of Arizona

2004-2007 Annual Psychopharmacology Review- Sleep Disorders Update
Single Presentation, University of Arizona

Selected Publications

Quan SF. The journal of clinical sleep medicine-moving forward.
J Clin Sleep Med. 2012 Dec 15;8(6):631. [PMID: 23243395]

Kushida CA, Nichols DA, Holmes TH, Quan SF, Walsh JK, Gottlieb DJ, Simon RD Jr, Guilleminault C, White DP, Goodwin JL, Schweitzer PK, Leary EB, Hyde PR, Hirshkowitz M, Green S, McEvoy LK, Chan C, Gevins A, Kay GG, Bloch DA, Crabtree T, Dement WC. Effects of Continuous Positive Airway Pressure on Neurocognitive Function in Obstructive Sleep Apnea Patients: The Apnea Positive Pressure Long-term Efficacy Study (APPLES).
Sleep. 2012 Dec 1;35(12):1593-602. [PMID: 23204602]

Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, Marcus CL, Mehra R, Parthasarathy S, Quan SF, Redline S, Strohl KP, Davidson Ward SL, Tangredi MM. Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the  Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. 
J Clin Sleep Med. 2012 Oct 15;8(5):597-619. [PMID: 23066376]

Quan SF. The lure of the impact factor and Journal of Clinical Sleep Medicine.
J Clin Sleep Med. 2012 Aug 15;8(4):355. [PMID: 22893764]

Redline S, Quan SF. Sleep apnea: a common mechanism for the deadly triad--cardiovascular disease, diabetes, and cancer?
Am J Respir Crit Care Med. 2012 Jul 15;186(2):123-4. [PMID: 22798414]

Archbold KH, Vasquez MM, Goodwin JL, Quan SF. Effects of sleep patterns and obesity on increases in blood pressure in a 5-year period: report from the Tucson Children's Assessment of Sleep Apnea Study.
J Pediatr. 2012 Jul;161(1):26-30. [PMID: 22284918]

Quan SF, Awad KM, Budhiraja R, Parthasarathy S. The Quest to Improve CPAP Adherence--PAP Potpourri is Still Not the Answer, but more research is needed.
J  Clin Sleep Med. 2012 Jun 15;8(3):345. [PMID: 22701396]

Quan SF. The Affordable Care Act: in the Supreme Court we trust.
J Clin Sleep Med. 2012 Jun 15;8(3):241. [PMID: 22701378]

Awad KM, Malhotra A, Barnet JH, Quan SF, Peppard PE. Exercise is associated with a reduced incidence of sleep-disordered breathing. 
Am J Med. 2012 May;125(5):485-90. [PMID: 22482846]

Quan SF, Buysse DJ, Ward SL, Harding SM, Iber C, Kapur VK, Rowley JA, Sateia  MJ, Silber MH, Sorscher AJ, Vaughn BV, Witmans M, Woodson BT, Zee P, Mills LE, Hess BJ. Development and growth of a large multispecialty certification examination: sleep medicine certification--results of the first three examinations.
J Clin Sleep Med. 2012 Apr 15;8(2):221-4. [PMID: 22505871]

Patel N, Sam A, Valentin A, Quan SF, Parthasarathy S. Refill rates of accessories for positive airway pressure therapy as a surrogate measure of long-term adherence.
J Clin Sleep Med. 2012 Apr 15;8(2):169-75. [PMID: 22505862]

Baldwin CM, Choi M, McClain DB, Celaya A, Quan SF. Spanish translation and cross-language validation of a sleep habits questionnaire for use in clinical and research settings.
J Clin Sleep Med. 2012 Apr 15;8(2):137-46. [PMID: 22505858]

Budhiraja P, Budhiraja R, Goodwin JL, Allen RP, Newman AB, Koo BB, Quan SF. Incidence of restless legs syndrome and its correlates. 
J Clin Sleep Med. 2012 Apr 15;8(2):119-24. [PMID: 22505854]

Budhiraja R, Parthasarathy S, Budhiraja P, Habib MP, Wendel C, Quan SF. Insomnia in patients with COPD.
Sleep. 2012 Mar 1;35(3):369-75. [PMID: 22379243]

Quan SF, Awad KM, Budhiraja R, Parthasarathy S. The quest to improve CPAP adherence--PAP potpourri is not the answer.
J Clin Sleep Med. 2012 Feb 15;8(1):49-50. [PMID: 22334809]

Awad KM, Drescher AA, Malhotra A, Quan SF. Effects of exercise and nutritional intake on sleep architecture in adolescents. 
Sleep Breath. 2012 Jan 31. [PMID: 22331514]

Parthasarathy S, Fitzgerald M, Goodwin JL, Unruh M, Guerra S, Quan SF. Nocturia, sleep-disordered breathing, and cardiovascular morbidity in a community-based cohort.
PLoS One. 2012;7(2):e30969. [PMID: 22328924]

Perfect MM, Patel PG, Scott RE, Wheeler MD, Patel C, Griffin K, Sorensen ST, Goodwin JL, Quan SF. Sleep, glucose, and daytime functioning in youth with type 1 diabetes.
Sleep. 2012 Jan 1;35(1):81-8. [PMID:22215921]

Brown MA, Goodwin JL, Silva GE, Behari A, Newman AB, Punjabi NM, Resnick HE, Robbins JA, Quan SF. The Impact of Sleep-Disordered Breathing on Body Mass Index (BMI): The Sleep Heart Health Study (SHHS).
Southwest J Pulm Crit Care. 2011 Dec 8;3:159-168.[PMID: 22288025]

Quan SF, Shaw PJ, Naidoo N, Haeggström E, Krueger JM, Church GM. Panel discussion: can there be a biomarker for sleepiness?
J Clin Sleep Med. 2011 Oct 15;7(5 Suppl):S45-8. [PMID: 22003333]

Quan SF. Finding a research path for the identification of biomarkers of sleepiness.
J Clin Sleep Med. 2011 Oct 15;7(5 Suppl):S4-5. [PMID: 22003331]

Silva GE, Vana KD, Goodwin JL, Sherrill DL, Quan SF. Identification of patients with sleep disordered breathing: comparing the four-variable screening tool, STOP, STOP-Bang, and Epworth Sleepiness Scales.
J Clin Sleep Med. 2011 Oct 15;7(5):467-72. [PMID: 22003341]

Silva GE, Goodwin JL, Parthasarathy S, Sherrill DL, Vana KD, Drescher AA, Quan SF. Longitudinal association between short sleep, body weight, and emotional and learning problems in Hispanic and Caucasian children.
Sleep. 2011 Sep 1;34(9):1197-205. [PMID: 21886357]

Drescher AA, Goodwin JL, Silva GE, Quan SF. Caffeine and screen time in adolescence: associations with short sleep and obesity.
J Clin Sleep Med. 2011 Aug 15;7(4):337-42. [PMID: 21897768]

Chen YJ, Jacobs WJ, Quan SF, Figueredo AJ, Davis AH. Psychophysiological determinants of repeated ventilator weaning failure: an explanatory model.
Am J Crit Care. 2011 Jul;20(4):292-302. [PMID: 21724633]

Quan SF. Return from the darkside--Sleep Medicine fellowship training: past, present and future.
J Clin Sleep Med. 2011 Jun 15;7(3):237. [PMID: 21677891]

Valentin A, Subramanian S, Quan SF, Berry RB, Parthasarathy S. Air leak is associated with poor adherence to autoPAP therapy.
Sleep. 2011 Jun 1;34(6):801-6. [PMID: 21629369]

Quan SF. The healthcare debate--is it misguided?
J Clin Sleep Med. 2011 Apr 15;7(2):133-4. [PMID: 21509326]

Chami HA, Resnick HE, Quan SF, Gottlieb DJ. Association of incident cardiovascular disease with progression of sleep-disordered breathing.
Circulation. 2011 Mar 29;123(12):1280-6. Epub 2011 Mar 14. [PMID: 21403097]

Quan SF, Chan CS, Dement WC, Gevins A, Goodwin JL, Gottlieb DJ, Green S, Guilleminault C, Hirshkowitz M, Hyde PR, Kay GG, Leary EB, Nichols DA, Schweitzer PK, Simon RD, Walsh JK, Kushida CA. The association between obstructive sleep apnea and neurocognitive performance--the Apnea Positive Pressure Long-term Efficacy Study (APPLES).
Sleep. 2011 Mar 1;34(3):303-314B. [PMID: 21358847]

Brown MA, Quan SF, Eichling PS. Circadian rhythm sleep disorder, free-running type in a sighted male with severe depression, anxiety, and agoraphobia.
J Clin Sleep Med. 2011 Feb 15;7(1):93-4. [PMID: 21344043]

Furet O, Goodwin JL, Quan SF. Incidence and Remission of Parasomnias among Adolescent Children in the Tucson Children's Assessment of Sleep Apnea (TuCASA) Study.
Southwest J Pulm Crit Care. 2011 Jan 1;2:93-101. [PMID: 21847446]

Poh CH, Allen L, Gasiorowska A, Navarro-Rodriguez T, Quan SF, Malagon I, Powers J, Willis MR, Ashpole N, Fass R. Conscious awakenings are commonly associated with Acid reflux events in patients with gastroesophageal reflux disease.
Clin Gastroenterol Hepatol. 2010 Oct;8(10):851-7. Epub 2010 Jun 1. [PMID: 20621628]

Budhiraja R, Budhiraja P, Quan SF. Sleep-disordered breathing and cardiovascular disorders.
Respir Care. 2010 Oct;55(10):1322-32; discussion 1330-2. Review. [PMID: 20875159]

Krystal AD, Zammit GK, Wyatt JK, Quan SF, Edinger JD, White DP, Chiacchierini RP, Malhotra A. The effect of vestibular stimulation in a four-hour sleep phase advance model of transient insomnia.
J Clin Sleep Med. 2010 Aug 15;6(4):315-21. [PMID: 20726278]

Gottlieb DJ, Yenokyan G, Newman AB, O'Connor GT, Punjabi NM, Quan SF, Redline S, Resnick HE, Tong EK, Diener-West M, Shahar E. Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study.
Circulation. 2010 Jul 27;122(4):352-60. Epub 2010 Jul 12. [PMID: 20625114]

Poh CH, Gasiorowska A, Allen L, Navarro-Rodriguez T, Mizyed I, Powers J, Moty B, Quan SF, Willis MR, Ashpole N, Malagon I, Fass R. Reassessment of the principal characteristics of gastroesophageal reflux during the recumbent period using integrated actigraphy-acquired information.
Am J Gastroenterol. 2010 May;105(5):1024-31. Epub 2009 Nov 10. [PMID: 19904242]

Goodwin JL, Vasquez MM, Silva GE, Quan SF. Incidence and remission of sleep-disordered breathing and related symptoms in 6- to 17-year old children--the Tucson Children's Assessment of Sleep Apnea Study.
J Pediatr. 2010 Jul;157(1):57-61. Epub 2010 Mar 20. [PMID: 20304429]

Poh CH, Gasiorowska A, Allen L, Navarro-Rodriguez T, Mizyed I, Powers J, Moty B, Quan SF, Willis MR, Ashpole N, Malagon I, Fass R. Reassessment of the principal characteristics of gastroesophageal reflux during the recumbent period using integrated actigraphy-acquired information.
Am J Gastroenterol. 2010 May;105(5):1024-31. Epub 2009 Nov 10. [PMID: 19904242]

Poh CH, Allen L, Malagon I, Gasiorowska A, Navarro-Rodriguez T, Powers J, Moty B, Willis MR, Quan SF, Fass R. Riser's reflux--an eye-opening experience.
Neurogastroenterol Motil. 2010 Apr;22(4):387-94. Epub 2010 Jan 5. [PMID: 20059700]

Gupta A, Sando S, Parthasarathy S, Quan SF. Information technology conduit as a portal to circumvent the graveyard shift.
J Clin Sleep Med. 2010 Apr 15;6(2):113-6. Review. [PMID: 20411685]

Lundy SM, Silva GE, Kaemingk KL, Goodwin JL, Quan SF. Cognitive Functioning and Academic Performance in Elementary School Children with Anxious/Depressed and Withdrawn Symptoms.
Open Pediatr Med Journal. 2010 Apr 14;4:1-9. [PMID: 20664711]

Archbold KH, Johnson NL, Goodwin JL, Rosen CL, Quan SF. Normative heart rate parameters during sleep for children aged 6 to 11 years.
J Clin Sleep Med. 2010 Feb 15;6(1):47-50. [PMID: 20191937]

Quan SF, Parthasarathy S, Budhiraja R. Healthy sleep education--a salve for obesity?
J Clin Sleep Med. 2010 Feb 15;6(1):18-9. [PMID: 20191933]

Budhiraja R, Quan SF, Punjabi NM, Drake CL, Dickman R, Fass R. Power spectral analysis of the sleep electroencephalogram in heartburn patients with or without gastroesophageal reflux disease: a feasibility study.
J Clin Gastroenterol. 2010 Feb;44(2):91-6. [PMID: 19661813]

Quan SF. Sleep medicine and graduate medical education--prospects for the future.
J Clin Sleep Med. 2009 Dec 15;5(6):497. [PMID: 20465013]

Monahan K, Storfer-Isser A, Mehra R, Shahar E, Mittleman M, Rottman J, Punjabi N, Sanders M, Quan SF, Resnick H, Redline S. Triggering of nocturnal arrhythmias by sleep- disordered breathing events.
J Am Coll Cardiol. 2009 Nov 3;54(19):1797-804. [PMID: 19874994]

Budhiraja R, Quan SF, Punjabi NM, Drake CL, Dickman R, Fass R. Power Spectral Analysis of the Sleep Electroencephalogram in Heartburn Patients With or Without Gastroesophageal Reflux Disease (GERD): A Feasibility Study.
J Clin Gastroenterol. 2009 Aug 5. [Epub ahead of print] [PMID: 19661813]

Silva GE, An MW, Goodwin JL, Shahar E, Redline S, Resnick H, Baldwin CM, Quan SF. Longitudinal evaluation of sleep-disordered breathing and sleep symptoms with change in quality of life: the Sleep Heart Health Study (SHHS).
Sleep. 2009 Aug 1;32(8):1049-57. [PMID: 19725256]

Rice A, Costy-Bennett S, Goodwin JL, Quan SF, Fregosi RF. Control of breathing in children with mild sleep apnoea: a six-year follow up study.
Eur Respir J. 2009 Jul 2. [Epub ahead of print] [PMID: 19574325]

O'Connor GT, Caffo B, Newman AB, Quan SF, Rapoport DM, Redline S, Resnick HE,
Samet J, Shahar E. Prospective study of sleep-disordered breathing and
hypertension: the Sleep Heart Health Study. Am J Respir Crit Care Med. 2009 Jun
15;179(12):1159-64. Epub 2009 Mar 5. [PMID: 19264976]

Quan SF. Work hours during residency training--the IOM speaketh.
J Clin Sleep Med. 2009 Feb 15;5(1):9-10. [PMID: 19317372]

Quan SF. Everywhere a conflict.
J Clin Sleep Med. 2008 Dec 15;4(6):531. [PMID: 19110879]

Ambrogio C, Koebnick J, Quan SF, Ranieri M, Parthasarathy S. Assessment of sleep in ventilator-supported critically III patients.
Sleep. 2008 Nov 1;31(11):1559-68. [PMID: 19014076]

Quan SF, Berry RB, Buysse D, Collop NA, Grigg-Damberger M, Harding SM, Iber C, McCall WV, Sateia MJ, Sheldon SH, Silber MH, Sorscher A, Ward SL, Veasey S, Woodson BT, Hess B, Kangilaski R. Development and results of the first ABMS subspecialty Certification Examination in Sleep Medicine.
J Clin Sleep Med. 2008 Oct 15;4(5):505-8. [PMID: 18853709]

Vasquez MM, Goodwin JL, Drescher AA, Smith TW, Quan SF. Associations of dietary intake and physical activity with sleep disordered breathing in the Apnea Positive Pressure Long-Term Efficacy Study (APPLES).
J Clin Sleep Med. 2008 Oct 15;4(5):411-8. [PMID: 18853696]

Guerra S, Sherrill DL, Kurzius-Spencer M, Venker C, Halonen M, Quan SF, Martinez FD. The course of persistent airflow limitation in subjects with and without asthma.
Respir Med. 2008 Oct;102(10):1473-82. Epub 2008 Aug 6. [PMID: 18684603]

Sharief I, Silva GE, Goodwin JL, Quan SF. Effect of sleep disordered breathing on the sleep of bed partners in the Sleep Heart Health Study.
Sleep. 2008 Oct 1;31(10):1449-56. [PMID: 18853943]

Quan SF, Budhiraja R, Parthasarathy S. Is there a bidirectional relationship between obesity and sleep-disordered breathing?
J Clin Sleep Med. 2008 Jun 15;4(3):210-1. [PMID: 18595432]

Quan SF. Guests and ghosts begone-guest authorship and ghostwriting and the Journal of Clinical Sleep Medicine.
J Clin Sleep Med. 2008 Jun 15;4(3):203. [PMID: 18595430]

Kushida CA, Chediak A, Berry RB, Brown LK, Gozal D, Iber C, Parthasarathy S, Quan SF, Rowley JA; Positive Airway Pressure Titration Task Force; American Academy of Sleep Medicine. Clinical guidelines for the manual titration of positive airway pressure in patients with obstructive sleep apnea.
J Clin Sleep Med. 2008 Apr 15;4(2):157-71. [PMID: 18468315]

Quan SF, Redline S. Hypopnea scoring in the Sleep Heart Health Study.
Chest. 2008 Apr;133(4):1054-5; discussion 1055. [PMID: 18398136]

Zhao Q, Sherrill DL, Goodwin JL, Quan SF. Association Between Sleep Disordered Breathing and Behavior in School-Aged Children: The Tucson Children's Assessment of Sleep Apnea Study.
Open Epidemiol J. 2008;1:1-9. [PMID: 18568089]

Schey R, Dickman R, Parthasarathy S, Quan SF, Wendel C, Merchant J, Powers J, Han B, van Handel D, Fass R. Sleep deprivation is hyperalgesic in patients with gastroesophageal  reflux disease.
Gastroenterology. 2007 Dec;133(6):1787-95. [PMID: 18054551]

Venker CC, Goodwin JL, Roe DJ, Kaemingk KL, Mulvaney S, Quan SF. Normative psychomotor vigilance task performance in children ages 6 to 11--the Tucson Children's Assessment of Sleep Apnea (TuCASA).
Sleep Breath. 2007 Dec;11(4):217-24. [PMID: 17333098]

Silva GE, Goodwin JL, Sherrill DL, Arnold JL, Bootzin RR, Smith T, Walsleben JA, Baldwin CM, Quan SF. Relationship between reported and measured sleep times:  the sleep heart health study (SHHS). 
J Clin Sleep Med. 2007 Oct 15;3(6):622-30. [PMID: 17993045]

Quan SF, O'connor GT, Quan JS, Redline S, Resnick HE, Shahar E, Siscovick D,Sherrill DL. Association of physical activity with sleep-disordered breathing.
Sleep Breath. 2007 Jan 13; [Epub ahead of print][PMID: 17221274]

Quan SF, Wright R, Baldwin CM, Kaemingk KL, Goodwin JL, Kuo TF, Kaszniak A, Boland LL, Caccappolo E, Bootzin RR. Obstructive sleep apnea-hypopnea and neurocognitive functioning in the Sleep Heart Health Study.
Sleep Med. 2006 Sep;7(6):498-507. Epub 2006 Jul 3. [PMID: 16815753]

Kushida CA, Nichols DA, Quan SF, Goodwin JL, White DP, Gottlieb DJ, Walsh JK, Schweitzer PK, Guilleminault C, Simon RD, Leary EB, Hyde PR, Holmes TH, Bloch DA, Green S, McEvoy LK, Gevins A, Dement WC.  The Apnea Positive Pressure Long-term Efficacy Study (APPLES): rationale, design, methods, and procedures.
J Clin Sleep Med. 2006 Jul 15;2(3):288-300. [PMID: 17561541]

Goodwin JL, Kaemingk KL, Mulvaney SA, Morgan WJ, Quan SF. Clinical screening of school children for polysomnography to detect sleep-disordered breathing--the Tucson Children's Assessment of Sleep Apnea study (TuCASA).
J Clin Sleep Med. 2005 Jul 15;1(3):247-54. [PMID: 16429591]

Parthasarathy S, Haynes PL, Budhiraja R, Habib MP, Quan SF. A national survey of the effect of sleep medicine specialists and American Academy of Sleep Medicine Accreditation on management of obstructive sleep apnea.
J Clin Sleep Med. 2006 Apr 15;2(2):133-42. [PMID: 17557485]

Quan SF, Katz R, Olson J, Bonekat W, Enright PL, Young T, Newman A. Factors associated with incidence and persistence of symptoms of disturbed sleep in an elderly cohort: the Cardiovascular Health Study.
Am J Med Sci. 2005 Apr;329(4):163-72. [PMID: 15832098]

Parthasarathy S, Habib M, Quan SF. How are automatic positive airway pressure and related devices prescribed by sleep physicians? A web-based survey.
J Clin Sleep Med. 2005 Jan 15;1(1):27-34. [PMID: 17561612]

Quan SF, Gersh BJ; National Center on Sleep Disorders Research; National Heart, Lung, and Blood Institute. Cardiovascular consequences of sleep-disordered breathing: past, present and future: report of a workshop from the National Center on Sleep Disorders Research and the National Heart, Lung, and Blood Institute.
Circulation. 2004 Mar 2;109(8):951-7. No abstract available. [PMID: 14993147]

Fregosi RF, Quan SF, Kaemingk KL, Morgan WJ, Goodwin JL, Cabrera R, Gmitro A.  Sleep-disordered breathing, pharyngeal size and soft tissue anatomy in children.
J Appl Physiol. 2003 Nov;95(5):2030-8. Epub 2003 Aug 1. [PMID: 12897029]

Kaemingk KL, Pasvogel AE, Goodwin JL, Mulvaney SA, Martinez F, Enright PL, Rosen GM, Morgan WJ, Fregosi RF, Quan SF.  Learning in children and sleep disordered breathing: findings of the Tucson Children's Assessment of Sleep Apnea (tuCASA) prospective cohort study.
J Int Neuropsychol Soc. 2003 Nov;9(7):1016-26. [PMID: 14738283]

Enright PL, Goodwin JL, Sherrill DL, Quan JR, Quan SF; Tucson Children's Assessment of Sleep Apnea study.  Blood pressure elevation associated with sleep-related breathing disorder in a community sample of white and Hispanic children: the Tucson Children's Assessment of Sleep Apnea study.
Arch Pediatr Adolesc Med. 2003 Sep;157(9):901-4. [PMID: 12963596]

Goodwin JL, Kaemingk KL, Fregosi RF, Rosen GM, Morgan WJ, Sherrill DL, Quan SF.  Clinical outcomes associated with sleep-disordered breathing in Caucasian and Hispanic children--the Tucson Children's Assessment of Sleep Apnea study (TuCASA).
Sleep. 2003 Aug 1;26(5):587-91. [PMID: 12938812]

Quan SF, Goodwin JL, Babar SI, Kaemingk KL, Enright PL, Rosen GM, Fregosi RF, Morgan WJ. Sleep architecture in normal Caucasian and Hispanic children aged 6-11 years recorded during unattended home polysomnography: experience from the Tucson Children's Assessment of Sleep Apnea Study (TuCASA).
Sleep Med. 2003 Jan;4(1):13-9. [PMID: 14592355]

Quan SF, Griswold ME, Iber C, Nieto FJ, Rapoport DM, Redline S, Sanders M, Young T; Sleep Heart Health Study (SHHS) Research Group.  Short-term variablility of respiration and sleep during unattended nonlaboratory polysomnogaphy--the Sleep Heart Health Study.
Sleep. 2002 Dec;25(8):843-9. [PMID: 12489889]

Goodwin JL, Enright PL, Kaemingk KL, Rosen GM, Morgan WJ, Fregosi RF, Quan SF.  Feasibility of using unattended polysomnography in children for research--report of the Tucson Children's Assessment of Sleep Apnea study (TuCASA).
Sleep. 2001 Dec 15;24(8):937-44. [PMID: 11766164]

Holberg CJ, Natrajan S, Cline MG, Quan SF. Familial Aggregation and Segregation Analysis of Snoring and Symptoms of Obstructive Sleep Apnea.
Sleep Breath. 2000;4(1):21-30. [PMID: 11894196]

Sherrill DL, Kotchou K, Quan SF. Association of physical activity and human sleep disorders.
Arch Intern Med. 1998 Sep 28;158(17):1894-8. [PMID: 9759685]

Quan SF, Howard BV, Iber C, Kiley JP, Nieto FJ, O'Connor GT, Rapoport DM, Redline S, Robbins J, Samet JM, Wahl PW.  The Sleep Heart Health Study: design, rationale, and methods.
Sleep. 1997 Dec;20(12):1077-85. [PMID: 9493915]

Dodge R, Cline MG, Quan SF. The natural history of insomnia and its relationship to respiratory symptoms.
Arch Intern Med. 1995 Sep 11;155(16):1797-800. [PMID: 7654114]

Klink ME, Dodge R, Quan SF. The relation of sleep complaints to respiratory symptoms in a general population.
Chest. 1994 Jan;105(1):151-4. [PMID: 8275723]

Reviews

Budhiraja R, Parthasarathy S, Quan SF. Endothelial dysfunction in obstructive sleep apnea.
J Clin Sleep Med. 2007 Jun 15;3(4):409-15. Review. [PMID: 17694731]

Redline S, Budhiraja R, Kapur V, Marcus CL, Mateika JH, Mehra R, Parthasarthy S, Somers VK, Strohl KP, Sulit LG, Gozal D, Wise MS, Quan SF. The scoring of respiratory events in sleep: reliability and validity.
J Clin Sleep Med. 2007 Mar 15;3(2):169-200. Review. [PMID: 17557426]


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