Faculty Profile

Lichao Chen, MD, PhD

Lichao Chen, MD, PhD
Instructor in Psychiatry, Harvard Medical School
Instructor, Department of Psychiatry, VA Boston Healthcare System

See publications

Society Memberships

Sleep Research Society
Society for Neuroscience

Research Unit(s)

Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System

Research Interests

My current research interest is to study the role of the orexin system in sleep regulation using both behavioral and molecular techniques.


Selected Publications

Chen L, McKenna JT, Leonard MZ, Yanagawa Y, McCarley RW, Brown RE. GAD67-GFP knock-in mice have normal sleep-wake patterns and sleep homeostasis.
Neuroreport. 2010 Feb. 21(3):216-220,2010. [PMID:20051926]

Chen L, Brown RE, McKenna JT, McCarley RW. Animal models of narcolepsy.
CNS Neurol Disord Drug Targets. 2009 Aug;8(4):296-308. [PMID: 19689311]

Chen L, Thakkar MM, Winston S, Bolortuya Y, Basheer R, McCarley RW. REM sleep changes in rats induced by siRNA-mediated orexin knockdown.
Eur J Neurosci. 2006 Oct;24(7):2039-48. [PMID: 17067300]

Chen L, Duricka D, Nelson S, Mukherjee S, Bohnet SG, Taishi P, Majde JA, Krueger JM. Influenza virus-induced sleep responses in mice with targeted disruptions in
neuronal or inducible nitric oxide synthases.
J Appl Physiol. 2004 Jul;97(1):17-28. [PMID: 15220315]

Chen L, Taishi P, Majde JA, Peterfi Z, Obal F Jr, Krueger JM. The role of nitric oxide synthases in the sleep responses to tumor necrosis factor-alpha.
Brain Behav Immun. 2004 Jul;18(4):390-8. [PMID: 15157956]

Chen L, Majde JA, Krueger JM. Spontaneous sleep in mice with targeted disruptions of neuronal or inducible nitric oxide synthase genes.
Brain Res. 2003 May 30;973(2):214-22. [PMID: 12738065]

Churchill L, Taishi P, Guan Z, Chen L, Fang J, Krueger JM. Sleep modifies glutamate decarboxylase mRNA within the barrel cortex of rats after a mystacial whisker trim.
Sleep. 2001 May 1;24(3):261-6. [PMID: 11322707]

Brandt JA, Churchill L, Guan Z, Fang J, Chen L, Krueger JM. Sleep deprivation but not a whisker trim increases nerve growth factor within barrel cortical neurons.
Brain Res. 2001 Apr 13;898(1):105-12. [PMID: 11292453]

Zhang Q, Wang SC, Qiao P, Hu QY, Chen LC, Wang YR. A study of the mechanism of L-NNA on sleep inhibition.
Sheng Li Xue Bao. 1997 Oct;49(5):585-8. Chinese. [PMID: 9813501]

Chen LC, Gu YH. Coding theories and analyzing methods of information contained in neuronal spike trains.
Sheng Li Ke Xue Jin Zhan. 1999 Apr;30(2):101-6. Chinese. [PMID: 12532800]

Books, Chapters, Reviews

Sorg BA, Tschirgi ML, Swindell S, Chen L, Fang J. Repeated formaldehyde effects in an animal model for multiple chemical sensitivity.
Ann N Y Acad Sci. 2001 Mar;933:57-67. Review. [PMID: 12000036]

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