Faculty Profile

Lawrence J. Epstein, MD

Lawrence J. Epstein, MD
Instructor in Medicine, Harvard Medical School
Associate Physician, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital

Administrative Title(s)

Program Director, Sleep Medicine Fellowship Program, Brigham & Women’s Hospital

See publications

Society Memberships

American Academy of Sleep Medicine (President, 2005-2006)
American College of Physicians
American College of Chest Physicians
American Thoracic Society

Research Unit(s)

Sleep Disorders Program, Division of Sleep Medicine, Brigham and Women's Hospital
Sleep Medicine Fellowship Program, Brigham and Women's Hospital


Donald Howard, MD, 1992-1994
Peter Fort, MD, 1993-1995  
Jan Westerman, MD, 1993-1995 
Najib Ayas, MD, 1999-2000
John Cronin, MD, 2002-2004
Kelly Carden, MD, 2002-2004
Milena Pavlova, MD, 2004-2005
Jeff Ellenbogen, MD, 2005-2007
Dennis Rosen, MD, 2005-2006
Pankaj Merchia, MD, 2005-2007
Ina Djonlagic, MD, 2006-2007
Shilpa Rahangdale, MD, 2006-2007
Josna Adusumilli, MD, 2007-2008
Mikhail Litinski, MD, 2007-2008
Maryann Deak, MD, 2008-2009
David Plante, MD, 2008-2009
Brain Abaluck, MD, 2009-2010
Muhammad Ali, MD, 2009-2010


1998-2005 Harvard Intensive Review of Internal Medicine. “Diagnosis and Treatment of Obstructive Sleep Apnea”

2003-2006 Brigham & Women’s Hospital’s Office Practice of Primary Care Medicine.  “Diagnosis and Treatment of Obstructive Sleep Apnea in the Clinic and In the Lab”

2007 American Academy of Sleep Medicine, Management of a Sleep Disorders Center:  Administrative, Legal & Health Policy Practices Course.  “A-STEP & Sleep Technologist Training”.

Selected Publications

Ayas NT, Epstein LJ, Lieberman SL, Tun CG, Larkin EK, Brown R, Garshick E. Predictors of loud snoring in persons with spinal cord injury.
J Spinal Cord Med. 2001 Spring;24(1):30-4. [PMID: 11587432]

Casserly LF, Chow N, Ali S, Gottlieb DJ, Epstein LJ, Kaufman JS. Proteinuria in obstructive sleep apnea.
Kidney Int. 2001 Oct;60(4):1484-9. [PMID: 11576363]

Epstein LJ, Jervis  OJ Jr, Henderson  JH 2nd, Sullivan M, Mohsenifar Z. Measurement of gastric P(CO2) as an index of tissue hypoxia during obstructive sleep apnea.
Respiration. 2001;68(1):28-34. [PMID: 11223727]

Epstein LJ, Dorlac GR. Cost-effectiveness analysis of nocturnal oximetry as a method of screening for sleep apnea-hypopnea syndrome.
Chest. 1998 Jan;113(1):97-103. [PMID: 9440575]

Loube DI, Strollo PJ, Epstein LJ, Davenport WL. The effect of quiet tidal breathing on lateral cephalometric measurements.
J Oral Maxillofac Surg. 1995 Oct;53(10):1155-9; discussion 1159-60. [PMID: 7562168]

Will MJ, Esther MS, Tiner BD, McAnear JT, Ingmundson P, Epstein L.  A Comparison of Cephalometric Analysis with Ethnicity in Obstructive Sleep Apnea Syndrome.
Sleep. 1995 Dec;18(10):873-5. [PMID: 8746394]

Epstein LJ, Strollo PJ Jr, Donegan RB, Delmar J, Hendrix C, Westbrook PR.  Obstructive sleep apnea in patients with human immunodeficiency virus (HIV) disease.
Sleep. 1995 Jun;18(5):368-76. [PMID: 7676171]

Epstein LJ, Meyer RD, Antonson S, Strigle SM, Mohsenifar Z. Persistence of Pneumocystis carinii in patients with AIDS receiving chemoprophylaxis.
Am J Respir Crit Care Med. 1994 Nov;150(5 Pt 1):1456-9. [PMID: 7952576]

Epstein LJ, Mohsenifar Z, Daar ES, Yeh V, Meyer RD. Clinical experience with atovaquone: a new drug for treating Pneumocystis carinii pneumonia.
Am J Med Sci. 1994 Jul;308(1):5-8. [PMID: 8010339]

Epstein LJ, Mohsenifar Z. Use of Nd:YAG laser in endobronchial granular cell myoblastoma.
Chest. 1993 Sep;104(3):958-60. [PMID: 8365322]

Belman MJ, Epstein LJ, Doornbos D, Elashoff JD, Koerner SK, Mohsenifar Z. Noninvasive determinations of the anaerobic threshold. Reliability and validity in patients with COPD.
Chest. 1992 Oct;102(4):1028-34. [PMID: 1395738]

Reviews, Books, Book Chapters, and Other Publications

Epstein LJ, Brown R.  Sleep Disorders in Spinal Cord Injury. 
In: Lin VW (ed), Spinal Cord Medicine; Principles and Practice, Second Edition.  New York: Demos, 2010;230-40.

Maher E, Epstein LJ.  Artifacts and Troubleshooting. 
Sleep Medicine Clinics. 2009;4:421:34.

Deak M, Epstein LJ.  The History of Polysomnography. 
Sleep Medicine Clinics. 2009;4:313:21.

Collop NA, Epstein LJ.  Entering the Age of Portable Monitoring. 
Journal of Clinical Sleep Medicine. 2008;4:303-4.

Epstein LJ, Medical Editor.  Improving Sleep; a guide to a good night’s rest.  Harvard Medical School Special Health Report.  Harvard Health Publications, 2007.

Rahangdale S, Epstein LJ. 2007. "Positive airway pressure therapy": Theory, indications, effectiveness, adverse effects.
In: Fundamentals of Sleep Technology, ed. N. Butkov and, T. Lee-Chiong. Lippincott Williams & Wilkins.

Epstein LJ, Mardon S. 2006. The Harvard Medical School guide to a good night’s sleep. New York: McGraw Hill.

Epstein LJ, Silber MH. AASM’s response to the ASAA letter to the editor.
J Clin Sleep Med. 2006;2:363-4.

Epstein LJ. Specialized sleep care benefits patients.
J Clin Sleep Med. 2006 Apr 15;2(2):143-4. [PMID: 17557486]

Epstein LJ, Stepanski EJ. Hurricanes Katrina and Rita - A call for assistance.  
J Clin Sleep Med. 2005;1:333.

Epstein LJ. Milestone Achieved: The specialty of sleep medicine.  
J Clin Sleep Med. 2005; 1:407-9.

Epstein LJ, Wagner PD, Kvale PA. Pulmonary physicians in the practice of sleep medicine.  A joint 3 society editorial appearing in the journals of the American Academy of Sleep Medicine, American Thoracic Society and the American College of Chest Physicians.
Sleep. 2005 28:1496-97.
American Journal of  Respiratory and Critical Care Medicine. 2005 172:1357-8. 
Chest. 2005 128:3788-90.

Epstein LJ, Medical Editor. 2005. Improving Sleep: A guide to a good night’s rest. Harvard Medical School Special Health Report. Harvard Health Publications.

Epstein LJ. Polysomnographic technololgists – troubled waters ahead?  
J Clin Sleep Med. 2005 Jan 15;1(1):14-5. [PMID: 17561608]

Epstein LJ, Brown R. 2003. "Sleep Disorders in Spinal Cord Injury." In Spinal Cord Medicine: Principles and Practice, ed. Lin VW, 169-177. New York: Demos.

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