Faculty Profile

Nancy L. Chamberlin, PhD


Associate Professor of Neurology, Harvard Medical School
Associate Professor, Department of Neurology, Beth Israel Deaconess Medical Center

See publications


Inter-office Mail Address

E/CLS 711

Email nchamber@bidmc.harvard.edu

Society Memberships

Society for Neuroscience
Sleep Research Society
American Physiological Society

Research Unit(s)

Systems Neurobiology Group, Beth Israel Deaconess Medical Center, Harvard Medical School
Respiratory and Anesthesia Translational Group

Trainees

Mark Henry 2009-2010
Lisa Kaplin 2009
Martina Grosse-Sundrup 2008
Sebastian Zaremba 2007
Philipp Fassbender 2006

Mentor(s)


Selected Publications

Eikermann M, Eckert DJ, Chamberlin NL, Jordan AS, Zaremba S, Smith S, Rosow C, Malhotra A. Effects of pentobarbital on upper airway patency during sleep.
Eur Respir J. 2009 Dec 23. [Epub ahead of print] PMID: 20032012 [PubMed - as supplied by publisher]

Eikermann M, Fassbender P, Zaremba S, Jordan AS, Rosow C, Malhotra A, Chamberlin NL. Pentobarbital dose-dependently increases respiratory genioglossus muscle activity while impairing diaphragmatic function in anesthetized rats.
Anesthesiology. 2009 Jun;110(6):1327-34. [PMID: 19417601]

Eikermann M, Zaremba S, Malhotra A, Jordan AS, Rosow C, Chamberlin NL. Neostigmine but not sugammadex impairs upper airway dilator muscle activity and breathing.
Br J Anaesth. 2008 Sep;101(3):344-9. Epub 2008 Jun 16. [PMID: 18559352]

Lu J, Nelson LE, Franks N, Maze M, Chamberlin NL, Saper CB. Role of endogenous sleep-wake and analgesic systems in anesthesia.
J Comp Neurol. 2008 Jun 1;508(4):648-62. [PMID: 18383504]

Eikermann M, Malhotra A, Fassbender P, Zaremba S, Jordan AS, Gautam S, White DP, Chamberlin NL. Differential effects of isoflurane and propofol on upper airway dilator muscle activity and breathing.
Anesthesiology. 2008 May;108(5):897-906. [PMID: 18431126]

Eikermann M, Fassbender P, Malhotra A, Takahashi M, Kubo S, Jordan AS, Gautam S, White DP, Chamberlin NL. Unwarranted administration of acetylcholinesterase inhibitors can impair genioglossus and diaphragm muscle function.
Anesthesiology. 2007 Oct;107(4):621-9. [PMID: 17893459]

Eikermann M, Jordan AS, Chamberlin NL, Gautam S, Wellman A, Lo YL, White DP, Malhotra A. The influence of aging on pharyngeal collapsibility during sleep.
Chest. 2007 Jun;131(6):1702-9. Epub 2007 Apr 5. [PMID: 17413053]

Chamberlin NL, Eikermann M, Fassbender P, White DP, Malhotra A. Genioglossus premotoneurons and the negative pressure reflex in rats.
J Physiol 2007; 579(Pt 2):515-526. [PMID: 17185342]

Arrigoni E, Chamberlin NL, Saper CB, McCarley RW. Adenosine inhibits basal forebrain cholinergic and noncholinergic neurons in vitro.
Neuroscience. 2006 Jun 30;140(2):403-13. Epub 2006 Mar 20. [PMID: 16542780]

Reviews

Saboisky JP, Chamberlin NL, Malhotra A. Potential therapeutic targets in obstructive sleep apnoea.
Expert Opin Ther Targets. 2009 Jul;13(7):795-809. Review. [PMID: 19530985]

Alfille PH, Merritt C, Chamberlin NL, Eikermann M. Control of perioperative muscle strength during ambulatory surgery.
Curr Opin Anaesthesiol. 2009 Sep 11. [Epub ahead of print] [PMID: 19752726]

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