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Lack of Exercise Can Disrupt the Body’s Rhythms

May 22, 2015



Frank A .J. L. Scheer, an assistant professor at Harvard Medical School (HMS) and director of the Medical Chronobiology Program at Brigham and Women’s Hospital (BWH), and Kun Hu, an assistant professor at HMS and director of the Medical Biodynamics Program at BWH, discuss new research that shows that lack of exercise and aging disrupt ‘healthy’ scale-invariant dynamics of physical activity, featured in The New York Times (read the full article here). Such scale invariance is thought to represent coupled feedback systems in biology that span wide time scales, from minutes to a day, and its disruption been linked to morbidity and mortality. Previous work in animals and humans by Dr. Hu, Dr. Scheer, and colleagues has shown that such scale invariance is critically dependent on functioning of the suprachiasmatic nucleus, the master circadian clock in the brain.

This recent work was done in collaboration with Changgui Gu, Claudia P. Coomans, Eugene Stanley, and senior author Johanna H. Meijer.

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