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Press Release

"Adverse Metabolic and Cardiovascular Consequences of Circadian Misalignment"

March 2, 2009



Brigham and Women's Hospital Press Release:

A recent study performed by Frank Scheer, PhD, and Steven Shea, PhD, of the Division of Sleep Medicine, identifies the potential cause of the increased risk for cardiovascular and metabolic disease in shift workers. Their research shows that misalignment between the internal biological clock and the sleep/wake and fasting/feeding cycles, known as circadian misalignment, results in hormonal and metabolic changes that, if chronically maintained, could explain the increased risk for obesity, high blood pressure, diabetes and cardiovascular disease frequently found among shift workers. These findings appear in the online Early Edition of Proceedings of the National Academy of Sciences during the week of March 2, 2009.

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Related Links
"Risky Business" NBC Nightly News (video)
"Night Shift Work Hard on the Heart" HealthDay
"Night Shift Makes Metabolism Go Haywire" Wired Science
"Night Shift Health" ScienCentral (video)
"Out-of-sync days throw heart and metabolism out of whack" Science News
"Researchers find potential cause of heart risks for shift workers" Harvard Science


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