Sleep Research Society &

American Academy of Sleep Medicine

Undergraduate, Graduate and Postgraduate Training Opportunities 

in Basic and Clinical Sleep Research and Sleep Medicine

2001 - V Edition


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Boston University School of Medicine


Sleep Research Laboratory

Department of Psychiatry

Boston University School of Medicine

Bldg. M-913, 715 Albany Street, Boston, MA 02118


Tel.: (617) 638-5863 and (617) 638-7160

Fax: (617) 638-5862.

Faculty (Name, Email address):

Subimal Datta, Ph.D. SUBIMAL@BU.EDU

Types of Training Available


Masters of Medical Science, Graduate Students (M.D. and Ph.D.)


Postdoctoral Research

Types of Funding Available

Research grants and Individual Fellowships

Current Trainees (Names and Email address)

Predoctoral Fellows:

Elissa H. Patterson

Eric E. Spoley

Trainees who have completed training [in the past five years] and current status (Name, Title, Institution, Email)

Donald F. Siwek, Assistant Professor, Department of Anatomy and Neurobiology, Sleep Research Laboratory, Boston University School of Medicine, Bldg. M-913, 715 Albany street, Boston, MA02118.

Primary Research and/or Clinical Focus of Laboratory

Cellular and Neurochemical mechanisms of REM sleep
Cellular Basis of Brainstem PGO wave generation
Mechanisms Underlying the Cognitive Function of Sleep

Technical Capabilities of Lab  

Polygraphic recordings
Intracerebral Microinjections of Drugs
Single cell Recordings
General Physiology and Anatomy
Learning and Memory Behavioral testing      

Primary Training Focus

       Animal Research (Rat)

Other Training Opportunities       

Behavioral Neuroscience in Humans

Representative Publications For the Last Five Years

Datta S and Hobson JA. Neuronal activity in the caudo-lateral peribrachial pons: relationship to PGO waves and rapid eye movements. J. Neurophysiol. 1994; 71:95-109.

Kobler JB, Datta S, Goyal RK, and Benecchi EJ. Innervation of the larynx, pharynx, and upper esophageal sphincter of the rat. J. Comp. Neurol. 1994; 349:129-147.

Datta S and Hobson JA. Suppression of ponto-geniculo-occipital waves by neurotoxic lesions of pontine caudo-lateral peribrachial cells. Neuroscience, 1995; 67:703-712.

Datta S. Neuronal activity in the peribrachial area: relationship to behavioral state control. Neurosci. Biobehav. Rev. 1995; 19:67-84.

Datta S. Patterson, E.H. and Siwek, D.F. Endogenous and exogenous nitric oxide in the pedunculopontine tegmentum induces sleep. Synapse 1997; 27:69-78.

Datta S and Siwek DF. Excitation of the brainstem pedunculopontine tegmentum choli-nergic cells induces wakefulness and REM sleep. J. Neurophysiol. 1997; 77:2975-2988.

Datta S. Cellular basis of pontine ponto-geniculo-occipital wave generation and modulation. Cell. Mol. Neurobiol. 1997; 17:341-365.

Datta S, Siwek DF, Patterson EH and Cipolloni PB. Localization of pontine PGO wave generation sites and their anatomical projections in the rat. Synapse 1998; 30:409-423.

Quattrochi JJ, Datta S and Hobson JA. Cholinergic and noncholinergic afferents of the caudolateral parabrachial nucleus: a role in the long-term enhancement of rapid eye movement sleep. Neuroscience 1998; 83:1123-1136.

Datta S, Patterson EH and Siwek DF. Brainstem afferents of the cholinoceptive pontine wave generation sites in the rat. Sleep Research Online 1999; 2:79-82.

Datta S. PGO wave generation: Mechanism and functional significance, in Rapid Eye Movement Sleep (B.N. Mallick and S. Inoue, eds.), Narosa Publishing House, 91-106 pg (1999).

Datta S, Patterson EH, Vincitore M, Tonkiss J, Morgane PJ and Galler JR. Prenatal protein malnourished rats show changes in sleep-wake behavior as adults. J. Sleep Res. 2000; 9:71-79.

Datta, S. and Hobson, JA. The rat as an experimental model for sleep neurophysiology. Behav. Neurosci. Behav. Neurosci. 2000, in press.

Datta S. Avoidance task training potentiates phasic pontine-wave density in the rat: A mechanism for sleep dependent plasticity. J. Neurosci. 2000, in press.

www link for the Lab

Faculty Research Interests

Subimal Datta, Ph.D. is an Associate Professor of Psychiatry and Behavioral Neuroscience, Director for the Sleep Research Laboratory at the Boston University School of Medicine. Dr. Datta is a Neurobiologist uses multidisciplinary techniques (Anatomy, Physiology, Pharmacology, Biochemistry, and Behavior) to study the basic mechanisms and functions of sleep. His research goals are: 1. to understand how single cells of the brain and their specific chemical signals (neurotransmitters and neuromodulators) are organized at the level of population ensembles to determine the global behavioral states of waking and sleep; 2. to study the neurophysiological and molecular mechanism of state-dependent learning and memory consolidation; and 3. to study the consequences of altered brain development in the behavioral states of wake-sleep cycle. Dr. Datta received number of national and international awards for his contribution to the sleep research. Dr. Datta’s research program is currently funded through funds from the NIH and Boston University.