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Rush-Presbyterian-St. Luke’s Medical Center


Biological Rhythms Research Laboratory

Rush-Presbyterian-St. Luke’s Medical Center

1645 West Jackson Blvd., Suite 425

Chicago, IL 60612



Phone: (312) 850-7788

Fax: (312) 850-7707


Faculty (Name, Email address)

Charmane I. Eastman, Ph.D.

Types of Training Available


Full-time summer and part-time year round research assistantships


Full-time research assistantships (good preparation for graduate school)


Ph.D.s and MD/Ph.Ds in the Neuroscience Graduate Program of Rush University and Rush Medical College


Research Positions

Types of Funding Available:

Research grants from the National Institutes of Health can support Research Assistantships and Postdoctoral Research Positions. Postdocs and predocs can also apply for fellowships from the National Institutes of Health, the National Sleep Foundation, and other agencies

Current Trainees (Names and Email address):

Postdoctoral Fellows:

Helen J. Burgess, Ph.D.

Research Assistants:

Stacy K. Martin           

Clifford Gazda           

Stephanie Crowley    

Trainees who have completed training [in the past five years] and current status (Name, Title, Institution, Email):

Katie Sharkey, Ph.D., Rush Medical College (completing M.D. as part of M.D./Ph.D. program),

Erin K. Baehr, Ph.D., Postdoctoral Research Fellow, Sleep Disorders Service and Research Center, Psychology Department, Rush-Presbyterian-St. Luke's Medical Center,

Marc Hébert, Ph.D., Postdoctoral Research Fellow, Royal Alexandra Hospital, Department of Ophthalmology, Edmonton, Alberta, Canada,

Primary Research and/or Clinical Focus of Laboratory

Human circadian rhythms
Phase-shifting effects of light, dark and melatonin
Sedative effects of melatonin

Technical Capabilities of Lab

Our newly constructed lab includes:
Night Shift room for running groups of subjects in simulated shift work studies with control of various light intensities and computerized performance testing.
"Lazy Boy" room for measuring circadian rhythms in groups of subjects seated for many hours in comfortable recliners. For example, we collect saliva samples in dim light for melatonin profiles.
2 bedrooms and bathroom with shower.
Video cameras and intercoms to supervise and communicate with subjects in the rooms listed above from the control room and kitchen.
Ambulatory monitors for recording body temperature and ambient light
Wrist monitors for recording activity and ambient light
Computer system for analyzing circadian temperature phase

Primary Training Focus

Human (Basic)
Human (Clinical Research)

Other Training Opportunities

Sleep Disorders Service and Research Center

Rosalind Cartwright, Ph.D., 

Edward Stepanski, Ph.D.,

James Wyatt, Ph.D.,

Representative Publications For the Last Five Years

Eastman, C.I., Boulos, Z., Terman, M., Campbell, S.S., Dijk, D.-J., & Lewy, A.J. Light treatment for sleep disorders: consensus report. VI. Shift work. J. Biol. Rhythms, 10, 157-164, 1995.

Stewart, K.T., Hayes, B.C., & Eastman, C.I. Light treatment for NASA shiftworkers. Chronobiology International, 12, 141-151, 1995.

Stewart, K.T., & Eastman, C.I. The light stuff: Shiftwork, circadian rhythms, and manned spaceflight. In: M.F. Holick & E.G. Jung (Ed.), Biologic Effects of Light 1995, Walter de Gruyter & Co., Berlin, 340-347, 1996.

Mitchell, P.J., & Hoese, E.K., Liu, L., Fogg, L.F., & Eastman, C.I. Conflicting bright light exposure during night shifts impedes circadian adaptation. J. Biol. Rhythms, 12, 5-15, 1997.

Martin, S.K., & Eastman, C.I. Medium-intensity light produces circadian rhythm adaptation to simulated night-shift work. Sleep, 21, 154-165, 1998.

Eastman, C.I., & Martin, S.K. How to use light and dark to produce circadian adaptation to night shift work. Annals of Medicine, 31: 87-98, 1999.

Hebert, M., Fleck, M.S., Martin, S.K., Fishman, G.A. & Eastman, C.I. Melatonin suppression by light depends on light history. Sleep, 22:S136-137, 1999.

Hebert, M., Martin, S.K., & Eastman, C.I. Nocturnal melatonin secretion is not suppressed by light exposure behind the knee in humans. Neuroscience Letters, 274: 127-130, 1999.

Baehr, E.K., Fogg, L.F., & Eastman, C.I. Intermittent bright light and exercise to entrain human circadian rhythms to night work. Am J Physiol, 277: R1598-R1604, 1999.

Sharkey, K., & Eastman, C.I. Melatonin improves circadian adaptation to simulated night shift work better than placebo. Sleep, 22:S6-7, 1999.

Baehr, E.K., Revelle, W, & Eastman, C.I. Individual differences in the phase and amplitude of the human circadian temperature rhythm: with an emphasis on morningness-eveningness. Journal of Sleep Research, 9:117-127, 2000.

Sharkey, K.M., & Eastman, C.I. Treatment of daytime sleep after night shift work with exogenous melatonin. Sleep, 23: A23-24, 2000.

Martin, S.K., & Eastman, C.I. When is Your DLMO? Sleep, 23: A179, 2000.

Sharkey, K.M. & Eastman, C.I. Phase-advancing human circadian rhythms with melatonin. Soc Light Treatment Biol Rhythms Abstracts, 12:9, 2000.

Hebert, M., Martin, S.K. & Eastman, C.I. Effect of light history on light sensitivity in humans. Abstracts of the Seventh Meeting of the Society for Research on Biological Rhythms. page 30, 2000.

Eastman, C.I., Martin, S.K. & Hebert, M. Failure of extraocular light to facilitate circadian rhythm reentrainment in humans. Chronobiology International, 17:807-826, 2000.

Sharkey, K.M., Fogg, L.F. and Eastman, C.I. Effects of melatonin administration on daytime sleep after simulated night shift work. Journal of Sleep Research, 10, 2001.

Burgess, H.J., Sharkey, K.M. and Eastman, C.I. How bright light, dark and melatonin can help shift workers. Sleep Medicine Reviews, in press.

www link for the Lab


Faculty Research Interests