Division of Sleep Medicine @ Harvard Medical School
Research Study Subject Recruitment
Many of the faculty of the HMS Division of Sleep Medicine conduct research in human subjects. If you are interested in participating in a research study, please call or send email to the contact person indicated for that study.
If after reviewing this information you have remaining general questions, please contact the Division using the contact form.
| Additional Links for Potential Study Subjects |
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| Important notice: Your Rights as a Research Participant |
| NIH Clinical Trial search service: ClincialTrials.gov |
| Partners Hospitals' Clincial Trial search: Clinical Trials @ Partners |
If after reviewing this information you have remaining general questions, please contact the Division using the contact form.
| Are You an Early Bird? Participate in a 21-Day Sleep Research Study. |
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| The Division of Sleep Medicine at Brigham & Women’s Hospital is seeking people to participate in a research study to understand how genes influence the sleep patterns of people who are early birds. Eligible Participants: - Healthy Men and Women - 18-30 years old - Not on medications (some birth control okay) Participation involves a 3-week screening process, a DNA sample taken from your blood, and 21 consecutive days and nights living at the hospital If you complete the entire study you will receive up to $4,375. Contact Alana 617-525-8434 or earlybird@rics.bwh.harvard.edu Location: Brigham and Women’s Hospital, Boston, MA Study title: Circadian and genetic evaluation of extreme sleep timing Faculty member submitting this notice: Jeanne F. Duffy, MBA, PhD IRB expiration: 08/14/2008 Return to Summary |
| Bi-Level Positive Airway Pressure device for Hypertension in Obstructive Sleep Apnea |
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| Participants use a breathing device at home for 8 weeks. Study staff measures effects on their blood pressure. Location: 1505 Commonwealth Ave, Sleep Health Center, Brighton, MA Faculty member submitting this notice: Atul Malhotra, MD Subject Recruitment Contact: Ashley Schomer Contact Email: hypap@partners.org Contact Phone: 724-387-3778 IRB expiration: 10/16/2008 Return to Summary |
| Breathing device for Hypertension |
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| Participants use a breathing device or listen to classical music at home for 8 weeks. Study staff measures effects on their blood pressure. Location: 1505 Commonwealth Ave, Sleep Health Center, Brighton, MA Faculty member submitting this notice: Atul Malhotra, MD Subject Recruitment Contact: Ashley Schomer Contact Email: hypap@partners.org Contact Phone: 724-387-3778 IRB expiration: 10/11/2008 Return to Summary |
| Control of Dynamic Attention |
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| Visual Attention Studies: The Brigham and Women’s Hospital Visual Attention Lab is seeking participants ages 18-55 with normal or corrected-to-normal eyesight for non-invasive vision research studies. The studies consist of computer administered tasks such as searching for a ‘target’ item. Participants have the opportunity to make between $50 and $100 ($10/hr) for participation in multiple studies. If interested, please call Mike at (617) 768-8814 or email at study@search.bwh.harvard.edu. Location: Visual Attention Lab 64 Sidney St. #170 Cambridge MA, 02139 Faculty member submitting this notice: Todd S. Horowitz, PhD IRB expiration: 6/13/2009 |
| CPAP Effect on Neuromuscular Response in OSA Patients |
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| Brigham and Women’s Hospital in Boston seeks 18 to 75 year old males and females (weight below 300 pounds) with newly diagnosed obstructive sleep apnea, who haven’t been treated but are willing to accept CPAP treatment, to participate in a research study investigating upper airway muscles and the influence of sleep. The study involves two nights stay in our sleep physiology lab. You will have your upper airway and airway muscles monitored while you breathe with the assistance of an iron long ventilator before and after sleep. Upper airway muscle fatigue will also be evaluated after sleep. You will receive $300.00 payment for participation. For more information please call (617) 732-8977 or e-mail at kschory@rics.bwh.harvard.edu. Location: BIDMC East Campus through the Clinical Research Center located at Feldberg 8 Study title: CPAP Effect on Neuromuscular Response in OSA Patients Faculty member submitting this notice: Atul Malhotra, MD IRB expiration: 4/26/2008 Return to Summary |
| Defining phenotypic traits in obstructive sleep apnea |
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Researchers at Brigham & Women’s Hospital Division of Sleep Medicine seek men and women with obstructive sleep apnea for a research study of airway anatomy, breathing control and muscle function during sleep. To participate you must: be between the ages of 21 and 65, have no lung problems and not take any medication which affects breathing or sleep (including birth control), use CPAP (a mask that blows air into your nose) on a nightly basis. You will be required for one daytime visit (approximately 2 hours) and three or four overnight stays in hospital. Receive up to $750 for participation. If you are interested in finding out more please call Scott at 617-732-8976. Location: BIDMC East Campus through the Clinical Research Center located at Feldberg 8 Study title: Defining phenotypic traits in obstructive sleep apnea Faculty member submitting this notice: Atul Malhotra, MD IRB expiration: 2/12/2009 Return to Summary |
| Do you have Insomnia? |
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| Brigham and Women's Hospital is conducting a research study testing the effects of a sleep medication and metabolism (how the body processes sugar). We are currently enrolling people between the ages of 25-55 who have insomnia. The study involves 9 visits, including 3 overnight stays. Compensation is dependent on the number of completed visits & ranges from $25 up to $1,800. To find out more contact: Shawn insomniastudy@rics.bwh.harvard.edu (617) 525-6490 Location: Brigham & Women's Hospital, Boston, MA Study title: The effects of eszopiclone treatment (3mg for two months) to counteract the adverse metabolic consequences of primary insomnia Faculty member submitting this notice: John W. Winkelman, M.D., Ph.D. and Orfeu Buxton, PhD IRB expiration: 8/23/08 Return to Summary |
| Do you usually sleep 7-9 hours per night? |
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| Brigham and Women’s Hospital is currently enrolling men & women who are 20-50 years of age for a research study of the impact of sleep disruption in a typical hospital setting on sleep and daytime alertness and performance. You must be currently sleeping on a regular schedule, not taking any medications, and available for an approximately 2-3 week study. You would need to make two screening visits, and be able to stay overnight for 3 days in the General Clinical Research Center (GCRC) for sleep recording and computerized testing. During your overnight stays, we will measure how sounds in a typical hospital setting affect alertness, mood, mental performance, and sleep. Receive up to $600 To find out more contact: Shawn at Soconnor4@partners.org or (617) 525-6479 Location: Brigham & Women's Hospital, Boston, MA Study title: Evidence Based Design Meets Evidence Based Medicine: Human Studies for Validating New Acoustic Guidelines for Healthcare Facilities Using a Collaborative and Trans-Disciplinary Approach for Improving Patient Outcomes Faculty member submitting this notice: Orfeu Buxton, PhD IRB expiration: 1/9/2009 Return to Summary |
| Do you Sleep Less than 7 Hours a Night? 28-Day Sleep Research Study Age 18-35 |
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| Brigham and Women’s Hospital Seeks Participants for a sleep research study who: • Routinely Sleep Less than 7 Hours a Night • Willing To Spend 28 Days and Nights Living In Our Facility • No Medications or Sleep Disorders Receive up to $5,090 For More Information: 617-732-7917 research@rics.bwh.harvard.edu Location: Brigham & Women's Hospital, Boston, MA Study title: Neurobiology of Individual Differences in Sleep Duration Faculty member submitting this notice: Daniel Aeschbach IRB expiration: 8/23/2008 Return to Summary |
| Genetic Associations of Restless Legs Syndrome and Periodic Limb Movements of Sleep |
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Do You Have Restless Legs Syndrome? Brigham and Women’s Hospital Sleep Health Center in Brighton is conducting a research study that is following up on the recent finding of a genetic marker for Restless Legs Syndrome (RLS). To further investigate the genetics of RLS, we are asking patients to give blood to determine if they have genes for RLS. We will then see if these genes affect certain aspects of the disorder and response to treatments. This study may help us learn about what causes RLS, and may help us guide future treatments. The study will require one visit to the Sleep Health Centers clinic located in Brighton, MA. The visit will take about 30 minutes. Participants will receive compensation for travel expenses to the clinic. At the study visit we will describe the research study to you, ask you questions about your sleep and your health, and take a sample of blood from a vein in your arm. To learn more about this study, please contact Lisa at the Sleep Health Center affiliated with Brigham and Women’s Hospital by calling (617) 783-1496 extension 115 or emailing SleepResearch@sleephealth.com Location: Brighton, MA Study title: Genetic Associations of Restless Legs Syndrome and Periodic Limb Movements of Sleep Faculty member responsible for this notice: John W. Winkelman, M.D., Ph.D. IRB expiration: 9/26/2008 Return to Summary |
| Improving Sleep to Lower Blood Pressure |
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| The Beth Israel Deaconess Medical Center is looking for women and men between the ages 25-65 who have been told by their doctor that they have blood pressure above normal, or who are on stable blood pressure lowering medication. You might be interested in participating in a research study which investigates the effect of improved sleep hygiene (e.g. timing of bedtimes, exercise, eating and drinking habits) on blood pressure. The study involves a 2-week at-home evaluation phase, a 6-week at-home intervention, and 2 overnight in-hospital stays, one before and one after the intervention phase. Payment for the study including screening, at-home evaluation and intervention phase, and 2 in-hospital stays will be $500. Location: Clinical Research Center at Beth Israel Deaconess Medical Center Study title: Restoring sleep homeostasis to lower BP: A behavioral prevention and treatment approach Faculty member submitting this notice: Monika Haack, Ph.D. Contact Email: BPStudy@bidmc.harvard.edu Contact Phone: (617) 667 0308 IRB expiration: 7/15/2008 Return to Summary |
| Independent contributions of OSA and obesity in Cardiovascular Disease |
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| VOLUNTEERS NEEDED FOR A RESEARCH STUDY ON SLEEP APNEA AND OBESITY You must be between 18 and 70 years old, obese, a non-smoker, on no medications for sleep or Viagra, Levitra, or cialis, with no known heart, lung, brain or psychiatric problems, not pregnant, not a diabetic, not on therapy for high cholesterol and willing to be studied during sleep (one overnight stay required). You will receive up to $300 for participation in the study, which lasts approximately one night and half a day. If interested, please call Susie at Brigham & Woman's Hospital, 617-732-8456. Location: BIDMC East Campus through the Clinical Research Center located at Feldberg 8 Study title: Independent contributions of OSA and obesity in Cardiovascular Disease Faculty member submitting this notice: Atul Malhotra, MD IRB expiration: 11/28/2008 Return to Summary |
| Melatonin supplementation in patients with Essential Hypertension |
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| ARE YOU TAKING ATENOLOL or METOPROLOL TO MANAGE HIGH BLOOD PRESSURE? You may be eligible to participate in a research study at Brigham and Women’s Hospital to see if melatonin supplementation can help lower your blood pressure. Earn up to $2,000.00 if you are: • 35-65 years of age • Taking at least 50 mg of Atenolol or at least 100 mg of Metoprolol per day • Otherwise healthy - Participants will undergo a medical screening, including a sleep screen, which can take up to 3 weeks. -After the screening, the study will take approximately 6 weeks during which you will spend two separate four-day stays at our facility at Brigham and Women's Hospital to monitor sleep, blood pressure, and various hormones. Contact Carolina at 617-278-0662 or highbp@rics.bwh.harvard.edu for more information. Location: Sleep Disorders Program @BI, Brigham and Women's Hospital Boston, MA 02115 Faculty member submitting this notice: Frank A.J.L. Scheer, PhD Subject Recruitment Contact: Erin Kelly or Carolina Smales Contact Email: highbp@rics.bwh.harvard.edu Contact Phone: 617-278-0924 (Erin) or 617-278-0662 (Carolina) IRB expiration: 1/16/2009 Return to Summary |
| Naps, Dreaming, and Spatial Memory |
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| Participation in this study involves being trained on a cognitive task, then either taking a short nap or remaining awake, and finally being tested again on a similar task later in the day. Pays $50 for approximately a 7-hour commitment. To qualify for participation, you must be a current student, age 18-30. For more information, contact Joseph Benavides (jbenavid@bidmc.harvard.edu). Location: Beth Israel Deaconess Medical Center East, Center for Sleep and Cognition Faculty member submitting this notice: Robert Stickgold, PhD Subject Recruitment Contact: Joseph Benavides Contact Email: jbenavid@bidmc.harvard.edu IRB expiration: 4/2/2009 Return to Summary |
| A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Determine the Efficacy and Safety of Topiramate in the Treatment of Sleep-Related Eating Disorder (SRED) |
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| Do you get out of bed to eat at night, after you have gone to sleep? Do episodes of repetitive eating at night feel out of your control? You may have Sleep-Related Eating Disorder, which can disrupt your sleep and health. Brigham and Women’s Hospital Sleep Health Center in Brighton is conducting a research study on an investigational medication for Sleep-Related Eating Disorder. Qualified participants can receive study medication and medical evaluation at no cost. If interested, please call Lisa at (617) 783-1496 x115 Or email SleepResearch@sleephealth.com Location: Brighton, MA Study title: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Determine the Efficacy and Safety of Topiramate in the Treatment of Sleep-Related Eating Disorder (SRED) Faculty member submitting this notice: John W. Winkelman, M.D., Ph.D. IRB expiration: 11/14/2008 Return to Summary |
| Research Study Participants Wanted |
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| We are looking for healthy volunteers to participate in 21-day research study at Beth Israel Deaconess Medical Center. The purpose of the study is to investigate the effects of breathing air with low levels of oxygen (like being on top of a mountain) on the human body. Metabolism, blood pressure, and nervous system activity will be studied. If you participate in this study you will sleep in a tent in which the air is similar to that on Mt. Rainier for 14 nights. You will need to spend every night from 9:00 pm on at Beth Israel Deaconess Medical Center. On some days you will be occupied by research studies; on others you will free to leave the hospital. During the study we will measure your blood pressure, heart rate, breathing, nervous system activity, and blood vessel function. In order to be an eligible participant in the study you must be between the ages of 18-64, healthy, and not on any medications. You must be free of tobacco products, drugs, and illegal substances. Total compensation of $2250 will be paid upon completion of the study. If interested, please contact Bethany Kulczewski at pulmonary.lab@gmail.com Location: Beth Israel Deaconess Medical Center, Boston, MA Study title: Role of local vasodilators and MSNA in mediating blood pressure following two week exposure to intermittent cyclic hypoxia Faculty member submitting this notice: Dr. J. Woodrow Weiss Contact email: pulmonary.lab@gmail.com IRB expiration: 9/16/2008 Return to Summary |
| Skill Learning and Pain Perception in Relationship to Insomnia |
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| The Beth Israel Deaconess Medical Center is looking for people between the ages of 21-60 years who either suffer from insomnia or who are good sleepers to participate in a study about the relationship between sleep quality, pain perception, and skill learning. Poor or insufficient sleep is a common problem that may affect the way we learn new skills and may even affect the way we feel pain. The study involves three visits: Visit 1 (about 2 hours) is an initial screening visit, where we will explain the study to you in detail and answer any questions you might have. If you qualify, you will then be set up with a sleep diary that you keep for two weeks and fill out every day. On Visit 2 (about 5-6 hours), we will take a blood and urine sample, and test your perception of pain. We will apply warmth, heat, and pressure to your hand/arm/foot, and will ask you to estimate the intensity of the different stimuli. Then, you will undergo a skill learning session involving responding to symbols on a computer screen in different positions. We will ask you to return to the hospital on the following day, Visit 3 (for about 0.5-1 hour), to repeat the skill learning test. The total time spent at the medical center will be approximately 9 hours. Payment for the study including 3 visits to the hospital and a 2-week at-home evaluation phase will be $140. Parking will also be compensated. Location: Clinical Research Center at Beth Israel Deaconess Medical Center, Boston, MA Study title: Pain perception and skill learning in insomniacs and normal sleepers Faculty member submitting this notice: Janet Mullington, PhD Contact Email: SleepQuality@bidmc.harvard.edu Contact Phone: (617) 667 0308 IRB expiration: 2/24/2009 Return to Summary |
| Time on Your Hands? Participate in a 39-day Sleep Research study! |
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| The Division of Sleep Medicine at Brigham & Women’s Hospital is seeking healthy men & women ages 55-70 who are not on medications to participate in a sleep research study. You will have a 3-week screening and then if you are eligible you will spend 39 consecutive days and nights living at the Hospital. If you complete the entire study you will receive up to $9,075 For more information, call 617-732-7991 or send an email to us at: Sleepstudy@partners.org Location: Brigham and Women's Hospital, Boston, MA Study title: Sleep, Aging and Circadian Rhythm Disorders Faculty member submitting this notice: Charles A. Czeisler, PhD, MD and Jeanne F. Duffy, MBA, PhD IRB expiration: 10/02/2008 Return to Summary |
| Women: Want to Learn More About Your Sleep? |
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| Must be 18-30 and healthy to qualify Brigham & Women’s Hospital seeks healthy women ages 18-30 to participate in a sleep research study. Participants will spend 39 consecutive days and nights living in our facility. Receive up to $9,075. Call (617) 732-7991 or email sleepstudy@partners.org Location: Brigham and Women's Hospital, Boston, MA Study title: Sleep, Aging and Circadian Rhythm Disorders Faculty member submitting this notice: Charles A. Czeisler, PhD, MD and Jeanne F. Duffy, MBA, PhD IRB expiration: 10/02/2008 Return to Summary |
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