Division of Sleep Medicine @ Harvard Medical School
Research Study Subject Recruitment
Many of the faculty of the HMS Division of Sleep Medicine conduct research in human subjects. If you are interested in participating in a research study, please call or send email to the contact person indicated for that study.
If after reviewing this information you have remaining general questions, please contact the Division using the contact form.
| Additional Links for Potential Study Subjects |
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| Important notice: Your Rights as a Research Participant |
| NIH Clinical Trial search service: ClincialTrials.gov |
| Partners Hospitals' Clinical Trial search: Clinical Trials @ Partners |
If after reviewing this information you have remaining general questions, please contact the Division using the contact form.
| Are You a Night Owl? Participate in a 21-Day Sleep Research Study. |
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| The Division of Sleep Medicine at Brigham & Women’s Hospital is seeking people to participate in a research study to understand how genes influence the sleep patterns of people who are night owls. Eligible Participants: - Healthy Men and Women - 18-30 years old - Not on medications (some birth control okay) Participation involves a 3-week screening process, a DNA sample taken from your blood, and 21 consecutive days and nights living at the hospital If you complete the entire study you will receive up to $4,375. Location: Brigham and Women's Hospital, Boston, MA Study title: Circadian & Genetic Evaluation of Extreme Sleep Timing Faculty member submitting this notice: Jeanne F. Duffy, M.B.A., Ph.D Contact Email: nightowl@rics.bwh.harvard.edu Contact Phone: David at 617-525-8434 IRB expiration: 7/10/2009 Return to Summary |
| Are You Taking Atenolol or Metoprolol to Manage High Blood Pressure? |
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| You may be eligible to participate in a research study at Brigham and Women’s Hospital to see if melatonin supplementation can help lower your blood pressure. Earn up to $2,000.00 if you are: • 35-65 years of age • Taking at least 25 mg Atenolol or at least 50 mg Metoprolol per day • Otherwise healthy Participants will undergo a medical screening, including a sleep screen, which can take up to 3 weeks. After the screening, the study will take approximately 6 weeks during which you will spend 8 days in our facility to monitor sleep, blood pressure, and various hormones. Location: Brigham and Women’s Hospital General Clinical Research Center Study title: Melatonin supplementation in patients with essential hypertension Faculty member submitting this notice: Frank Scheer, PhD Contact Email: highbp@rics.bwh.harvard.edu Contact Phone: Erin at 617-278-0924 IRB expiration: 1/14/2010 Return to Summary |
| Are You Working the Night Shift? |
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| Do you find you are excessively sleepy when you work the night shift? If you’re a night worker who experiences difficulty sleeping during your off-work hours and find that you are excessively sleepy during your night shifts you may be eligible for a research study. The Division of Sleep Medicine at the Brigham and Women's Hospital is enrolling subjects 20-50 years of age who are currently working the night shift for a study of the effects of an FDA-approved sleep medication. You must be currently working at least 5 night shifts per month, and at least 3 of them must be consecutive. You would need to make three screening visits, three separate study visits (two overnight) and take this FDA-approved sleep medication. Compensation is dependent on the number of completed visits and ranges from: $50 up to $1200. Location: Brigham and Women’s Hospital Study Title:Effects of daytime eszopiclone administration in shift workers on overnight wakefulness during a subsequent simulated nightshift Faculty member submitting this notice: Orfeu M. Buxton, PhD Contact Email: nightwork@rics.bwh.harvard.edu Contact Phone: Dan at 617-525-6490 IRB expiration: 2/4/2010 Return to Summary |
| The Effect of Surgically Induced Weight Loss on Cardiovascular Abnormalities in Obese Subjects with and without Obstructive Sleep Apnea |
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| VOLUNTEERS NEEDED FOR A RESEARCH STUDY ON SLEEP APNEA AND OBESITY You must be between 18 and 70 years old, obese with untreated sleep apnea, a non- smoker, on no medications for sleep, not taking Viagra, Levitra, or Cialis, no known heart, lung, brain or psychiatric problems, not pregnant, not a diabetic and willing to be studied during sleep (3 overnight stays required). You will receive up to $900 for participation in the study, which lasts approximately one night and half a day on three separate occasions over the course of one year. If interested, please call Karen at Brigham & Woman’s hospital, 617-732-8977. Location: Brigham and Women’s Hospital General Clinical Research Center Study Title: The Effect of Surgically Induced Weight Loss on Cardiovascular Abnormalities in Obese Subjects with and without Obstructive Sleep Apnea Faculty member submitting this notice: Atul Malhotra, MD IRB expiration: 11/18/2009 Return to Summary |
| The Effect of CPAP Therapy on Cardiovascular Abnormalities in Obese subjects with Obstructive Sleep Apnea |
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| VOLUNTEERS NEEDED FOR A RESEARCH STUDY ON SLEEP APNEA AND OBESITY You must be between 18 and 70 years old, obese with untreated sleep apnea, on no medications for sleep, not taking Viagra, Cialis, or Levitra, no known heart, lung, brain or psychiatric problems, not diabetic, not pregnant and willing to be studied during sleep (3 overnight stays required). You will receive up to $900 for participation in the study, which lasts approximately one night and half a day on three separate occasions over the course of one year. Please contact Karen Stevenson at 617-732-8977 or KESTEVENSON@PARTNERS.ORG, BRIGHAM AND WOMEN’S HOSPITAL. Location: Brigham and Women’s Hospital General Clinical Research Center Study Title: The Effect of CPAP Therapy on Cardiovascular Abnormalities in Obese subjects with Obstructive Sleep Apnea Faculty member submitting this notice: Atul Malhotra, MD IRB expiration: 11/03/2009 Return to Summary |
| Control of Dynamic Attention |
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| Visual Attention Studies: The Brigham and Women’s Hospital Visual Attention Lab is seeking participants ages 18-55 with normal or corrected-to-normal eyesight for non-invasive vision research studies. The studies consist of computer administered tasks such as searching for a ‘target’ item. Participants have the opportunity to make between $50 and $100 ($10/hr) for participation in multiple studies. If interested, please call Mike at (617) 768-8814 or email at study@search.bwh.harvard.edu. Location: Visual Attention Lab 64 Sidney St. #170 Cambridge MA, 02139 Faculty member submitting this notice: Todd S. Horowitz, PhD IRB expiration: 6/13/2009 Return to Summary |
| Defining Phenotypic Traits in Obstructive Sleep Apnea |
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| Researchers at Brigham and Women's Hospital Division of Sleep Medicine seek healthy men and women with obstructive sleep apnea for a research study of airway anatomy, breathing control and muscle function during sleep. To participate you must: • be between the ages of 21 and 65 • have no lung problems • not take any medication which affects breathing or sleep (including birth control) • use CPAP on a nightly basis • be able to commit to 3-4 overnight studies within 1 month's period of time Receive up to $750 for participation. For information on participating in this study, call Lauren Hess @ 617-732-8976 for a brief preliminary phone interview. Location: Brigham and Women’s Hospital General Clinical Research Center Study Title: Defining phenotypic traits in obstructive sleep apnea Faculty member submitting this notice: Atul Malhotra, MD Contact Phone: Lauren at 617-732-8976 IRB expiration: 1/06/2010 Return to Summary |
| Do you have 8 days to spare? Looking for healthy volunteers ages 18-50! |
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| The Division of Sleep Medicine at Brigham and Women’s Hospital is looking for healthy volunteers ages 18-50 to participate in an 8 day sleep research study. Participation would involve at least three screening visits as well as spending 8 consecutive days and nights at the hospital. The study is being conducted to determine how different colors of light affect the body clock. Eligible Participants: *Healthy men and women *Ages 18-50 *Not on medications Receive up to $1,675 Location: Brigham and Women's Hospital, Boston, MA Study title: Evaluation of Photic Countermeasures for Circadian Entrainment of Neurobehavioral Performance and Sleep-Wake Regulation Before and During Spaceflight Faculty member submitting this notice: Jeanne F. Duffy, M.B.A., Ph.D for Charles A. Czeisler, Ph.D., M.D. Contact Email: eightdaystudy@partners.org Contact Phone: David at 617-525-7597 IRB expiration: 1/14/2010 Return to Summary |
| Do You Have INSOMNIA? |
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| Are you between the ages of 21-65? Brigham & Woman’s Hospital is looking for people who have been diagnosed with insomnia to participate in a research study. The study involves approximately 2 weeks of at home assessments and one 9 hour visit in our laboratory. Up to 4 screening visits may be required prior to beginning the study. Receive up to $300 at the completion of the study Location:Brigham and Women's Hospital Study Title: Assessment of circadian phase for the diagnosis and treatment of sleep phase insomnia Faculty member submitting this notice: Stephen Lockley, PhD Contact for this notice: Julia, jshekleton@partners.org, (617) 732 6460 IRB expiration: 6/17/2010 Return to Summary |
| Improving Sleep to Lower Blood Pressure |
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| The Beth Israel Deaconess Medical Center is looking for women and men between the ages 25-65 who have been told by their doctor that they have blood pressure above normal, or who are on stable blood pressure lowering medication. You might be interested in participating in a research study which investigates the effect of improved sleep hygiene (e.g. timing of bedtimes, exercise, eating and drinking habits) on blood pressure. The study involves a 2-week at-home evaluation phase, a 6-week at-home intervention, and 2 overnight in-hospital stays, one before and one after the intervention phase. Payment for the study including screening, at-home evaluation and intervention phase, and 2 in-hospital stays will be $500. Location: Clinical Research Center at Beth Israel Deaconess Medical Center Study title: Restoring sleep homeostasis to lower BP: A behavioral prevention and treatment approach Faculty member submitting this notice: Monika Haack, Ph.D. Contact Email: BPStudy@bidmc.harvard.edu Contact Phone: (617) 667 0308 IRB expiration: 5/26/2009 Return to Summary |
| Looking for a Challenge? Try a Sleep Study! |
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| Participants needed for 9 Day Sleep Research Study at Brigham and Women’s Hospital! Are you a healthy? Are you between the ages of 18-30 years old? Are you a non-smoker? Do you sleep about 8 hours a night? THEN YOU SHOULD TRY A SLEEP STUDY! Live in a lab for 9 days/nights, 24/7 and…RECEIVE UP TO $1,960 ** 3-5 week screening process, up to 5 outpatient visits before entering the study ** Location: Brigham and Women's Hospital, Boston, MA Study title: Light, Sleep, Performance and Circadian Rhythms Faculty member submitting for this notice: Steven W. Lockley, PhD Contact for this notice: Elizabethat 617-732-4311 IRB Expiration: 2/3/2010 Return to Summary |
| Need a Timeout? Do a 2 Day Sleep Research Study! |
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Complete 4 screening visits then live in the lab for just 2 days! Receive up to $350 -Healthy sleepers -Ages 18-30 -Non-smokers -No Medications Interested? Contact Us! Location: Brigham and Women's Hospital, Boston, MA Study title: Short-Wavelength Countermeasure for Circadian Desynchrony Faculty member submitting this notice: Steven W. Lockley, PhD Contact Phone: Elizabeth at 617-732-4311 IRB expiration: 5/5/2010 Return to Summary |
| A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Determine the Efficacy and Safety of Topiramate in the Treatment of Sleep-Related Eating Disorder (SRED) |
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| Do you get out of bed to eat at night, after you have gone to sleep? Do episodes of repetitive eating at night feel out of your control? You may have Sleep-Related Eating Disorder, which can disrupt your sleep and health. Brigham and Women’s Hospital Sleep Health Center in Brighton is conducting a research study on an investigational medication for Sleep-Related Eating Disorder. Qualified participants can receive study medication and medical evaluation at no cost. If interested, please call Lisa at (617) 783-1496 x115 Or email SleepResearch@sleephealth.com Location: Brighton, MA Study title: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Determine the Efficacy and Safety of Topiramate in the Treatment of Sleep-Related Eating Disorder (SRED) Faculty member submitting this notice: John W. Winkelman, M.D., Ph.D. IRB expiration: 10/06/2009 Return to Summary |
| Skill Learning and Pain Perception in Relationship to Insomnia |
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| The Beth Israel Deaconess Medical Center is looking for people between the ages of 21-60 years who either suffer from insomnia or who are good sleepers to participate in a study about the relationship between sleep quality, pain perception, and skill learning. Poor or insufficient sleep is a common problem that may affect the way we learn new skills and may even affect the way we feel pain. The study involves three visits: Visit 1 (about 2 hours) is an initial screening visit, where we will explain the study to you in detail and answer any questions you might have. If you qualify, you will then be set up with a sleep diary that you keep for two weeks and fill out every day. On Visit 2 (about 5-6 hours), we will take a blood and urine sample, and test your perception of pain. We will apply warmth, heat, and pressure to your hand/arm/foot, and will ask you to estimate the intensity of the different stimuli. Then, you will undergo a skill learning session involving responding to symbols on a computer screen in different positions. We will ask you to return to the hospital on the following day, Visit 3 (for about 0.5-1 hour), to repeat the skill learning test. The total time spent at the medical center will be approximately 9 hours. Payment for the study including 3 visits to the hospital and a 2-week at-home evaluation phase will be $140. Parking will also be compensated. Location: Clinical Research Center at Beth Israel Deaconess Medical Center, Boston, MA Study title: Pain perception and skill learning in insomniacs and normal sleepers Faculty member submitting this notice: Janet Mullington, PhD Contact Email: SleepQuality@bidmc.harvard.edu Contact Phone: (617) 667 0308 IRB expiration: 1/25/2010 Return to Summary |
| Shine a LIGHT on your inner clock! |
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| Participants needed for 11 Day Sleep Research Study on the effects of light on sleep at Brigham and Women's Hospital. *Must be male, 18-30 years old *Not on any medications Receive up to $2,000 Location: Brigham and Women's Hospital, Boston, MA Study title: Spectral sensitivity of non-image-forming responses to light in humans Faculty member submitting this notice: Steven W. Lockley, Ph.D. Contact Phone: (617) 525-8636 IRB Expiration: 2/19/2010 Return to Summary |
| Time on Your Hands? Participate in a 39-day Sleep Research study! |
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| The Division of Sleep Medicine at Brigham & Women's Hospital is seeking healthy men & women ages 55-70 who are not on medications to participate in a sleep research study. You will have a 3-week screening and then if you are eligible you will spend 39 consecutive days and nights living at the Hospital. If you complete the entire study you will receive up to $9,075 For more information, call 617-732-7991 or send an email to us at: Sleepstudy@partners.org Location: Brigham and Women's Hospital, Boston, MA Study title: Sleep, Aging and Circadian Rhythm Disorders Faculty member submitting this notice: Charles A. Czeisler, PhD, MD and Jeanne F. Duffy, MBA, PhD IRB expiration: 8/05/2009 Return to Summary |
| Women: Want to Learn More About Your Sleep? |
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| Must be 18-30 and healthy to qualify Brigham & Women’s Hospital seeks healthy women ages 18-30 to participate in a sleep research study. Participants will spend 39 consecutive days and nights living in our facility. Receive up to $9,075. Call (617) 732-7991 or email sleepstudy@partners.org Location: Brigham and Women's Hospital, Boston, MA Study title: Sleep, Aging and Circadian Rhythm Disorders Faculty member submitting this notice: Charles A. Czeisler, PhD, MD and Jeanne F. Duffy, MBA, PhD IRB expiration: 8/05/2009 Return to Summary |
| Research Study Participants Needed! |
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| The Beth Israel Deaconess Medical Center is looking for healthy volunteers to participate in a 16-day research study. The purpose of the study is to investigate the relationship between sleep restriction (decreased sleep time) and insulin resistance (how the body handles blood sugar level). Your body’s insulin sensitivity, measurements of blood pressure, and nervous system activity will be studied. If you participate in this study you will live and sleep in the study lab at Beth Israel Deaconess Medical Center for 16 days/15 nights. For 9 of the nights, you may be required to sleep for only 4 hours per night. You may have visitors while in the study, but you will be unable to leave the study lab to go home. During the study we will measure your blood sugar level, blood pressure, heart rate, nervous system activity, and blood vessel function. We will also perform overnight sleep studies to assess your sleep and breathing on four nights during the 15 night period. To be eligible to participate in this study you must be between the ages of 18-64, healthy, with a regular sleep schedule, and not taking any medications for diabetes or blood pressure. You must be free of tobacco products, drugs, and illegal substances. Total compensation of $3000 will be paid after you have completed the study protocol If interested, please contact Bethany Kulczewski at pulmonary.lab@gmail.com. Location: Beth Israel Deaconess Medical Center Study title: The effect of chronic partial sleep restriction on insulin resistance Faculty member responsible for this notice: Bethany Kulczewski IRB expiration: 9/21/2009 Return to Summary |
| Research Study Participants Wanted |
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| We are looking for healthy volunteers to participate in 21-night research study at Beth Israel Deaconess Medical Center. The purpose of the study is to investigate the effects of breathing air with low levels of oxygen (like being on top of a mountain) on the human body. Metabolism, blood pressure, and nervous system activity will be studied. If you participate in this study you will sleep in a tent in which the air is similar to that on Mt. Rainier for 14 nights. You will need to spend every night from 9:00 pm on at Beth Israel Deaconess Medical Center. On seven separate days you will be occupied by research studies; on others you will free to leave the hospital. During the study we will measure your blood pressure, heart rate, breathing, nervous system activity, and blood vessel function. In order to be an eligible participant in the study you must be between the ages of 18-64, healthy, and not on any medications. You must be free of tobacco products, drugs, and illegal substances. Total compensation of $2350 will be paid upon completion of the study. If interested, please contact Bethany Kulczewski at pulmonary.lab@gmail.com. Any phone calls to our office will not receive a response. Location: Beth Israel Deaconess Medical Center Study Title: Role of local vasodilators and MSNA in mediating blood pressure following two week exposure to intermittent cyclic hypoxia Faculty member submitting this notice: Bethany Kulczewski IRB expiration: 7/27/2009 Return to Summary |
| Volunteers aged 55+ who want to learn about sleep needed |
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| Brigham and Women’s Hospital’s Division of Sleep Medicine is inviting men and women aged 55-80 to participate in a research study. The study tests how exposure to light impacts the timing and quality of sleep and hormones. You must be healthy to qualify. Participants will spend 8 consecutive days and nights living in a private room at BWH. Receive up to $2,175. Contact Becky at 617 732-7294 or sleep@rics.bwh.harvard.edu Location: BWH, Boston, MA Study Title: Disrupted Sleep in the Elderly: Light Exposure Studies Faculty member submitting this notice: Jeanne F. Duffy, M.B.A., Ph.D IRB expiration: 2/25/2010 Return to Summary |
| Would you like to participate in a study of the effects of light on your internal clock? |
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| We are currently looking for healthy men and women between the ages of 18 and 30 to participate in a 14 day sleep research study. Participants must be healthy, presently taking no medication, and have no sleep problems. If you meet these qualifications and have 14 days and nights free to live at Brigham and Women’s Hospital, then you may be eligible to participate. Receive up to $2,950 Call us at 617-732-8093 brightlights@partners.org Location: Brigham and Women's Hospital Study Title: Adaptation of the Human Circadian System to Previous Light Exposure Faculty member submitting this notice: Anne-Marie Chang IRB expiration: 12/10/2009 |
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