Division of Sleep Medicine @ Harvard Medical School

Trainee Profile

Melissa A. St. Hilaire, MS

Computational Research Associate, Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital

Other Affiliation(s)

Graduate student, Department of Cognitive and Neural Systems, Boston University

See publications

Address

Division of Sleep Medicine
221 Longwood Avenue, BLI-4
Boston, MA 02115
USA

Inter-office Mail Address

BLI-438

Phone 617-278-0620
Fax 617-732-4015

Email msthilaire@rics.bwh.harvard

Research Unit(s)

Analytic and Modeling Group, Division of Sleep Medicine, Brigham & Women's Hospital

Research Interests

Mathematical modeling of photic and non-photic effects on the human circadian system, melatonin, non-visual circadian photoreception, and inter-individual differences. Computational and neural models integrating the effect of sleep and circadian rhythms on cognitive function.

Mentor(s)

Elizabeth B. Klerman, MD, PhD
Daniel H. Bullock, PhD

Selected Publications

St Hilaire MA, Gronfier C, Zeitzer JM, Klerman EB. A physiologically based mathematical model of melatonin including ocular light suppression and interactions with the circadian pacemaker.
J Pineal Res. 2007 Oct;43(3):294-304. [PMID: 17803528]

St Hilaire MA, Klerman EB, Khalsa SB, Wright KP Jr, Czeisler CA, Kronauer RE. Addition of a non-photic component to a light-based mathematical model of the human circadian pacemaker.
J Theor Biol. 2007 Aug 21;247(4):583-99. [PMID: 17531270]

Klerman EB, St Hilaire MA. On mathematical modeling of circadian rhythms, performance, and alertness.
J Biol Rhythms. 2007 Apr;22(2):91-102. Review. [PMID: 17440211]

Indic P, Forger DB, St Hilaire MA, Dean DA 2nd, Brown EN, Kronauer RE, Klerman
EB, Jewett ME. Comparison of amplitude recovery dynamics of two limit cycle oscillator models of the human circadian pacemaker.
Chronobiol Int. 2005;22(4):613-29. [PMID: 16147894]