Division of Sleep Medicine @ Harvard Medical School
Faculty Profile
Orfeu M. Buxton, PhD
Instructor in Medicine, Harvard Medical School
Associate Neuroscientist, Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital
Administrative Title(s)
Training Coordinator, Division of Sleep Medicine
Address
221 Longwood Ave, Suite BLI-438KBoston, MA 02115
USA
Inter-office Mail Address
BWH Division of Sleep Medicine, BLI-438KFax 617-507-9177
Email Orfeu@HMS.Harvard.edu
Society Memberships
Society for Research of Biological RhythmsSleep Research Society
American Physiological Society
Endocrine Society
National Postdoctoral Association
Research Unit(s)
Circadian Group,
Division of Sleep Medicine, Brigham and Women's Hospital
Harvard Work Hours, Health, and Safety Group
Division of Sleep Medicine, Brigham and Women's Hospital
Harvard Work Hours, Health, and Safety Group
Research Funding
CURRENT
U01 5186989-01 Berkman (PI) 09/30/2008-09/29/2013
Subcontract from the Harvard School of Public Health NIH/NIA
“Evaluating the Health Benefits of Workplace Policies and Practices - Phase II”
The NIH and CDC formed the Work, Family, and Health Network (WFHN). During Phase 1, WFHN designed and conducted multiple pilot and feasibility studies. For Phase 2, the WFHN is implementing an innovative intervention based on Phase I pilot studies that is designed to increase family-supportive supervisor behaviors and employee control over work using a group randomized experimental design.
Role: subcontract Principal Investigator
P01 AG009975 Czeisler (PI) 09/01/2006-06/30/2011
NIH/NIA Program Project
“Sleep Aging and Circadian Rhythm Disorders”
Project 3 “Metabolic Aging: Endocrine and Cardiovascular Consequences Of Sleep Restriction”
Project #3 on ‘metabolic aging’ seeks to understand the endocrine and cardiovascular consequences of sleep restriction in both young and older subjects.
Role: Project Leader
ESRC-0977 (Buxton, PI) 04/01/2008-03/30/2010
Sepracor, Inc.
“Effects of daytime eszopiclone administration in shift workers on overnight wakefulness during a subsequent simulated nightshift”
The goal of this project is to determine whether improving daytime sleep quality in shiftworkers improves subsequent nighttime wakefulness and neurobehavioral performance.
Role: PI
R01 HL094806 Scheer (PI) 07/01/2009-11/30/2013
NIH
“Mechanisms underlying adverse health consequences of shift work”
The goal of the present proposal is to determine the effect of simulated shift work on physiological changes that increase susceptibility to the development of diabetes, obesity, and cardiovascular disease and to determine whether this effect is amplified in individuals with pre-diabetes.
Role: Co-investigator
COMPLETED
Grant (Berkman PI) 02/01/2007-04/30/2009
Alfred P. Sloan Foundation
Longitudinal Analyses Linking Workplace Flexibility to Physical Health Outcomes
The goal of this project is to determine the longitudinal relationships between work-related factors and Health Outcomes.
FA9550-06-0080/ O5NL132 Klerman (PI) 02/01/2006-11/30/2008
Air Force Office of Sponsored Research
“Interaction of chronic sleep restriction and circadian misalignment on sleep and neuro-cognitive performance: developing a new model of sleep homeostasis”
The goals of the project are (1) to determine the interaction of chronic sleep restriction and circadian misalignment on sleep and neurocognitive performance, and (2) incorporate the results into our mathematical model of human circadian rhythms and neurobehavioral performance.
Role: Investigator
ESRC-0004 Winkelman (PI) 08/15/2005-10/31/2008
Sepracor Inc.
“The effects of eszopiclone treatment (3mg for two months) to counteract the adverse metabolic consequences of primary insomnia”
This investigator-initiated project examines the reversibility of the effects of chronic primary insomnia on metabolic function.
Role: co-PI and Project Leader
Facilities Guidelines Institute (Solet, PI) 08/10/2007-10/31/2008
Subcontract from Cambridge Health Alliance Buxton (PI)
[Phase II] “Evidence Based Design Meets Evidence Based Medicine: Human Studies for Validating New Acoustic Guidelines for Healthcare Facilities Using a Collaborative and Trans-Disciplinary Approach for Improving Patient Outcomes”
The goal of the second research phase of this investigator-initiated research program is the implementation of a virtual soundscape environment for experiments on human subjects to demonstrate effects of the standard hospital room environment.
Role: subcontract Principal Investigator (subcontract from Cambridge Health Alliance)
The Center for Health Design/C.H.E.R. (Solet, PI) 10/01/2007-10/31/2008
Subcontract from Cambridge Health Alliance, Buxton (PI)
[Phase III] “Evidence Based Design Meets Evidence Based Medicine: Human Studies for Validating New Acoustic Guidelines for Healthcare Facilities Using a Collaborative and Trans-Disciplinary Approach for Improving Patient Outcomes”
The purpose of this project is to test the hypothesis that exposure to an acoustic environment adhering to evidence-based acoustical guidelines will evoke fewer physiologic arousals and be more conducive to sleep.
Role: subcontract Principal Investigator (subcontract from Cambridge Health Alliance)
NIH / NIA (Berkman, PI), Subcontract from the Harvard School of Public Health 2007-2008
“Family-Responsive Workplace Policies & Practice in Small Businesses with Low-Wage and Racially/Ethnically Diverse Workers”. The goal of our interdisciplinary research network is to identify workplace practices and policies that impact the health of low-wage employees and their families and dependents so as to design effective work-based interventions to improve health outcomes.
NIH / NIA (P.I.: Orfeu M. Buxton, Ph.D., subcontract via UCLA Biodemography Center) 2006-2007
Title: Comparison of different methods for measuring HbA1c in epidemiologic studies
NIH / NIOSH (Co-PIs: Leslie Hammer, PhD, Ellen Kossek, PhD) 2005-2007
Development of a Behavioral Measure of Supervisor Support for Work and Families
RWJ Health & Society Program, Harvard School of Public Health 2005-2007
(P.I.: Orfeu M. Buxton, PhD)
Sleep and Stress as Mediators of the Socioeconomic Status
and Body Mass Index (SES-BMI) Gradient among Adults
Cephalon, Inc. (investigator-initiated clinical trial, (P.I.: Orfeu M. Buxton, PhD) 2004-2007
Sleep Restriction, Impaired Glucose Metabolism, and Performance: The effects of
modafinil to counteract the adverse metabolic consequences of sleep restriction
Cephalon, Inc. (investigator-initiated clinical trial, (P.I.: Orfeu M. Buxton, PhD) 2004-2006
Effects of Tiagabine on Growth Hormone and Sleep in Older Persons
U01 5186989-01 Berkman (PI) 09/30/2008-09/29/2013
Subcontract from the Harvard School of Public Health NIH/NIA
“Evaluating the Health Benefits of Workplace Policies and Practices - Phase II”
The NIH and CDC formed the Work, Family, and Health Network (WFHN). During Phase 1, WFHN designed and conducted multiple pilot and feasibility studies. For Phase 2, the WFHN is implementing an innovative intervention based on Phase I pilot studies that is designed to increase family-supportive supervisor behaviors and employee control over work using a group randomized experimental design.
Role: subcontract Principal Investigator
P01 AG009975 Czeisler (PI) 09/01/2006-06/30/2011
NIH/NIA Program Project
“Sleep Aging and Circadian Rhythm Disorders”
Project 3 “Metabolic Aging: Endocrine and Cardiovascular Consequences Of Sleep Restriction”
Project #3 on ‘metabolic aging’ seeks to understand the endocrine and cardiovascular consequences of sleep restriction in both young and older subjects.
Role: Project Leader
ESRC-0977 (Buxton, PI) 04/01/2008-03/30/2010
Sepracor, Inc.
“Effects of daytime eszopiclone administration in shift workers on overnight wakefulness during a subsequent simulated nightshift”
The goal of this project is to determine whether improving daytime sleep quality in shiftworkers improves subsequent nighttime wakefulness and neurobehavioral performance.
Role: PI
R01 HL094806 Scheer (PI) 07/01/2009-11/30/2013
NIH
“Mechanisms underlying adverse health consequences of shift work”
The goal of the present proposal is to determine the effect of simulated shift work on physiological changes that increase susceptibility to the development of diabetes, obesity, and cardiovascular disease and to determine whether this effect is amplified in individuals with pre-diabetes.
Role: Co-investigator
COMPLETED
Grant (Berkman PI) 02/01/2007-04/30/2009
Alfred P. Sloan Foundation
Longitudinal Analyses Linking Workplace Flexibility to Physical Health Outcomes
The goal of this project is to determine the longitudinal relationships between work-related factors and Health Outcomes.
FA9550-06-0080/ O5NL132 Klerman (PI) 02/01/2006-11/30/2008
Air Force Office of Sponsored Research
“Interaction of chronic sleep restriction and circadian misalignment on sleep and neuro-cognitive performance: developing a new model of sleep homeostasis”
The goals of the project are (1) to determine the interaction of chronic sleep restriction and circadian misalignment on sleep and neurocognitive performance, and (2) incorporate the results into our mathematical model of human circadian rhythms and neurobehavioral performance.
Role: Investigator
ESRC-0004 Winkelman (PI) 08/15/2005-10/31/2008
Sepracor Inc.
“The effects of eszopiclone treatment (3mg for two months) to counteract the adverse metabolic consequences of primary insomnia”
This investigator-initiated project examines the reversibility of the effects of chronic primary insomnia on metabolic function.
Role: co-PI and Project Leader
Facilities Guidelines Institute (Solet, PI) 08/10/2007-10/31/2008
Subcontract from Cambridge Health Alliance Buxton (PI)
[Phase II] “Evidence Based Design Meets Evidence Based Medicine: Human Studies for Validating New Acoustic Guidelines for Healthcare Facilities Using a Collaborative and Trans-Disciplinary Approach for Improving Patient Outcomes”
The goal of the second research phase of this investigator-initiated research program is the implementation of a virtual soundscape environment for experiments on human subjects to demonstrate effects of the standard hospital room environment.
Role: subcontract Principal Investigator (subcontract from Cambridge Health Alliance)
The Center for Health Design/C.H.E.R. (Solet, PI) 10/01/2007-10/31/2008
Subcontract from Cambridge Health Alliance, Buxton (PI)
[Phase III] “Evidence Based Design Meets Evidence Based Medicine: Human Studies for Validating New Acoustic Guidelines for Healthcare Facilities Using a Collaborative and Trans-Disciplinary Approach for Improving Patient Outcomes”
The purpose of this project is to test the hypothesis that exposure to an acoustic environment adhering to evidence-based acoustical guidelines will evoke fewer physiologic arousals and be more conducive to sleep.
Role: subcontract Principal Investigator (subcontract from Cambridge Health Alliance)
NIH / NIA (Berkman, PI), Subcontract from the Harvard School of Public Health 2007-2008
“Family-Responsive Workplace Policies & Practice in Small Businesses with Low-Wage and Racially/Ethnically Diverse Workers”. The goal of our interdisciplinary research network is to identify workplace practices and policies that impact the health of low-wage employees and their families and dependents so as to design effective work-based interventions to improve health outcomes.
NIH / NIA (P.I.: Orfeu M. Buxton, Ph.D., subcontract via UCLA Biodemography Center) 2006-2007
Title: Comparison of different methods for measuring HbA1c in epidemiologic studies
NIH / NIOSH (Co-PIs: Leslie Hammer, PhD, Ellen Kossek, PhD) 2005-2007
Development of a Behavioral Measure of Supervisor Support for Work and Families
RWJ Health & Society Program, Harvard School of Public Health 2005-2007
(P.I.: Orfeu M. Buxton, PhD)
Sleep and Stress as Mediators of the Socioeconomic Status
and Body Mass Index (SES-BMI) Gradient among Adults
Cephalon, Inc. (investigator-initiated clinical trial, (P.I.: Orfeu M. Buxton, PhD) 2004-2007
Sleep Restriction, Impaired Glucose Metabolism, and Performance: The effects of
modafinil to counteract the adverse metabolic consequences of sleep restriction
Cephalon, Inc. (investigator-initiated clinical trial, (P.I.: Orfeu M. Buxton, PhD) 2004-2006
Effects of Tiagabine on Growth Hormone and Sleep in Older Persons
Brief biography
Dr. Buxton joined the Division of Sleep Medicine in 2003 as an Associate Neuroscientist at Brigham & Women's Hospital with an appointment to the Harvard Medical School Faculty as an Instructor. To study the health consequences of sleep loss, and to extend recent findings associating insufficient or poor quality sleep with obesity, diabetes, and cardiovascular disease, he founded a Sleep and Metabolism Research Program within the Division of Sleep Medicine. Successful aging is a central focus of this work. Ongoing interdisciplinary human studies involve sleep loss, aging, and insomnia, as well as neurobehavioral performance, learning and memory consolidation, and health disparities. Dr. Buxton is a member of the Work, Family, and Health Network.
After earning a B.S. in Behavioral Neuroscience from the University of Pittsburgh and a stint as a small business owner, Dr. Buxton earned a doctoral degree in Neuroscience from Northwestern University, Evanston, Illinois, working with Professors Eve Van Cauter and Fred Turek. He obtained post-doctoral training in sleep and endocrinology with Dr. Van Cauter at the University of Chicago.
Dr. Buxton co-founded the National Postdoctoral Association, a member-driven organization that provides a unique, national voice for postdoctoral scholars. In the Harvard Division of Sleep Medicine, Dr. Buxton serves as Training Coordinator and Chair of the Education Committee.
Dr. Buxton joined the Division of Sleep Medicine in 2003 as an Associate Neuroscientist at Brigham & Women's Hospital with an appointment to the Harvard Medical School Faculty as an Instructor. To study the health consequences of sleep loss, and to extend recent findings associating insufficient or poor quality sleep with obesity, diabetes, and cardiovascular disease, he founded a Sleep and Metabolism Research Program within the Division of Sleep Medicine. Successful aging is a central focus of this work. Ongoing interdisciplinary human studies involve sleep loss, aging, and insomnia, as well as neurobehavioral performance, learning and memory consolidation, and health disparities. Dr. Buxton is a member of the Work, Family, and Health Network.
After earning a B.S. in Behavioral Neuroscience from the University of Pittsburgh and a stint as a small business owner, Dr. Buxton earned a doctoral degree in Neuroscience from Northwestern University, Evanston, Illinois, working with Professors Eve Van Cauter and Fred Turek. He obtained post-doctoral training in sleep and endocrinology with Dr. Van Cauter at the University of Chicago.
Dr. Buxton co-founded the National Postdoctoral Association, a member-driven organization that provides a unique, national voice for postdoctoral scholars. In the Harvard Division of Sleep Medicine, Dr. Buxton serves as Training Coordinator and Chair of the Education Committee.
Selected Publications
Buxton OM, Malarick K, Wang W, Seeman T. Changes in dried blood spot Hb A1c with varied postcollection conditions.
Clin Chem. 2009 May;55(5):1034-6. Epub 2009 Mar 19. [PMID: 19299546]
Winkelman JW, Buxton OM, Jensen JE, Benson KL, O'Connor SP, Wang W, Renshaw PF. Reduced brain GABA in primary insomnia: preliminary data from 4T proton magnetic resonance spectroscopy (1H-MRS).
Sleep. 2008 Nov 1;31(11):1499-506. [PMID: 19014069]
Buxton OM, Lee CW, L'Hermite-Balériaux M, Turek FW, Van Cauter E. Exercise elicits phase shifts and acute alterations of melatonin levels that vary with circadian phase.
Am J Physiol 2003; 284 (Regulatory, Integrative, and Comparative 3):R714-R724. [PMID: 12571075]
Cunningham J, Buxton OM, Weiss R. Circadian variation in Cushing's disease and pseudo-Cushing's states by analysis of cortisol and adrenocorticotropin pulsatility.
J Endocrinological Investigation 2002; 25(9):791-9. [PMID: 12398238]
Buxton OM, Copinschi G, Onderbergen AV, Van Cauter E. A benzodiazepine hypnotic facilitates the adaptation of human circadian rhythms and sleep-wake homeostasis to an 8-hour delay shift simulating westward jet lag.
Sleep 2000; 23(7):915-27. [PMID: 11083601]
Horton TH, Buxton OM, Losee-Olson S, Turek FW. Twenty-four-hour profiles of serum leptin in Siberian and golden hamsters: Photoperiodic and diurnal variations.
Hormones and Behavior 2000; 37(4):388-98. [PMID: 10860682]
Valentinuzzi VS, Buxton OM, Chang AM, Scarbrough K, Ferrari EAM, Takahashi JS, Turek FW. Locomotor response to an open field during C57BL/6J active and inactive phases: differences dependent on conditions of illumination.
Physiology & Behavior 2000; 69(3):269-75. [PMID: 10869592]
Buxton OM, L'Hermite-Balériaux Turek FW, Van Cauter E. Daytime naps in darkness phase shift the human circadian rhythms of melatonin and thyrotropin secretion.
Am J Physiol 2000; 278 (Regulatory, Integrative, and Comparative 2):R373-82. [PMID: 10666138]
Naylor E, Buxton OM, Bergmann BM, Easton A, Zee PC, Turek FW. Effects of aging on sleep in the golden hamster.
Sleep 1998; 21(7):687-93. [PMID: 11286344]
Scheen AL, Buxton OM, Jison M, Van Reeth O, Leproult R, L'Hermite-Balériaux M, Van Cauter E. Effects of exercise on neuroendocrine secretion and glucose regulation at different times of day.
Am J Physiol 1998; 274 (Endocrinology and Metabolism 37):E1040-9. [PMID: 9611154]
Leproult R, Copinschi G, Buxton O, Van Cauter E. Sleep loss results in an elevation of cortisol levels the next evening.
Sleep 1997; 20(10):865-70. [PMID: 9415946]
Buxton OM, Frank SA, L'Hermite-Balériaux M, Leproult R, Turek FW, Van Cauter E. Roles of intensity and duration of nocturnal exercise in causing phase delays of human circadian rhythms.
Am J Physiol 1997; 273 (Endocrinology and Metabolism 36):E536-42. [PMID: 9316443]
Reviews, Book Chapters, and Editorials
“Single Slide Sets to Accompany the SRS Basics of Sleep Guide (version 1.1).” Charles J. Amlaner, Orfeu M. Buxton, editors. Sleep Research Society Educational Programs Committee. 2008.
“Slide Sets to Accompany the SRS Basics of Sleep Guide.” Charles J.
Amlaner, Orfeu M. Buxton, editors.
Sleep Research Society Educational Programs Committee. 2007.
"Evidence-Based Design: The new AIA Guidelines on Noise and Privacy," Sykes, D.; Rockstroh, R.; Solet, J.; Buxton, O. Pg 47-49, Healthcare Design 09.06, Volume 6, Number 5, September 2006, www.hcdmagazine.com.
Czeisler, CA. OM Buxton, and SB Khalsa. The human circadian timing system and sleep-wake regulation. In, Principles and Practices of Sleep Medicine. M Kryger, T Roth, W Dement eds., 2005.
O'Connor PJ, SD Youngstedt, OM Buxton, and MD Breus. FIMS position statement on air travel and performance in sports. Fèdèration Internationale de Mèdecine du Sport (FIMS) Position Statement #16, 2004, pp-1-12. Available at URL: http://www.fims.org/files/311417173/PS16%20Air%20travel%20March%202004.pdf.
Shawn D. Youngstedt, Orfeu M. Buxton. Jet Lag and Athletic Performance.
Amer J Sports Med. 2003;5:219-226.
Orfeu M. Buxton and Stephen Gasior. You've got the data! Now advocate for change! Science NextWave. April 2002. http://nextwave.sciencemag.org/cgi/content/full/2002/04/16/2
Orfeu M. Buxton, Karine Spiegel, and Eve Van Cauter. Modulation of endocrine function and metabolism by sleep and sleep loss. In: T. Lee-Chiong, M. Carskadon, M. Sateia, vol. eds., Sleep Medicine 2002; 59-69.
Orfeu M. Buxton and Stephen Gasior. Surveying Postdocs: A tale from the trenches.
Science NextWave. January 2002. http://nextwave.sciencemag.org/cgi/content/full/2002/01/03/5.
Eve Van Cauter and Orfeu M. Buxton. Circadian Modulation of Endocrine Secretion. In: J. Takahashi, F.W. Turek, R.Y. Moore, vol. eds., Handbook of Neurophysiology, 2001; 685-714.
Joaquin Recio, J.M. Míguez, Orfeu M. Buxton, Etienne Challet. Synchronizing circadian rhythms in early infancy.
Medical Hypotheses. 1997 Sep;49(3):229-34. [PMID: 9293467]
Orfeu M. Buxton, Mireille L'Hermite-Balériaux, Ulrich Hirschfeld, and Eve Van Cauter. Acute and delayed effects of exercise on human melatonin secretion.
J Biol Rhythms. 1997 Dec;12(6):568-74. [PMID: 9406031]
Clin Chem. 2009 May;55(5):1034-6. Epub 2009 Mar 19. [PMID: 19299546]
Winkelman JW, Buxton OM, Jensen JE, Benson KL, O'Connor SP, Wang W, Renshaw PF. Reduced brain GABA in primary insomnia: preliminary data from 4T proton magnetic resonance spectroscopy (1H-MRS).
Sleep. 2008 Nov 1;31(11):1499-506. [PMID: 19014069]
Buxton OM, Lee CW, L'Hermite-Balériaux M, Turek FW, Van Cauter E. Exercise elicits phase shifts and acute alterations of melatonin levels that vary with circadian phase.
Am J Physiol 2003; 284 (Regulatory, Integrative, and Comparative 3):R714-R724. [PMID: 12571075]
Cunningham J, Buxton OM, Weiss R. Circadian variation in Cushing's disease and pseudo-Cushing's states by analysis of cortisol and adrenocorticotropin pulsatility.
J Endocrinological Investigation 2002; 25(9):791-9. [PMID: 12398238]
Buxton OM, Copinschi G, Onderbergen AV, Van Cauter E. A benzodiazepine hypnotic facilitates the adaptation of human circadian rhythms and sleep-wake homeostasis to an 8-hour delay shift simulating westward jet lag.
Sleep 2000; 23(7):915-27. [PMID: 11083601]
Horton TH, Buxton OM, Losee-Olson S, Turek FW. Twenty-four-hour profiles of serum leptin in Siberian and golden hamsters: Photoperiodic and diurnal variations.
Hormones and Behavior 2000; 37(4):388-98. [PMID: 10860682]
Valentinuzzi VS, Buxton OM, Chang AM, Scarbrough K, Ferrari EAM, Takahashi JS, Turek FW. Locomotor response to an open field during C57BL/6J active and inactive phases: differences dependent on conditions of illumination.
Physiology & Behavior 2000; 69(3):269-75. [PMID: 10869592]
Buxton OM, L'Hermite-Balériaux Turek FW, Van Cauter E. Daytime naps in darkness phase shift the human circadian rhythms of melatonin and thyrotropin secretion.
Am J Physiol 2000; 278 (Regulatory, Integrative, and Comparative 2):R373-82. [PMID: 10666138]
Naylor E, Buxton OM, Bergmann BM, Easton A, Zee PC, Turek FW. Effects of aging on sleep in the golden hamster.
Sleep 1998; 21(7):687-93. [PMID: 11286344]
Scheen AL, Buxton OM, Jison M, Van Reeth O, Leproult R, L'Hermite-Balériaux M, Van Cauter E. Effects of exercise on neuroendocrine secretion and glucose regulation at different times of day.
Am J Physiol 1998; 274 (Endocrinology and Metabolism 37):E1040-9. [PMID: 9611154]
Leproult R, Copinschi G, Buxton O, Van Cauter E. Sleep loss results in an elevation of cortisol levels the next evening.
Sleep 1997; 20(10):865-70. [PMID: 9415946]
Buxton OM, Frank SA, L'Hermite-Balériaux M, Leproult R, Turek FW, Van Cauter E. Roles of intensity and duration of nocturnal exercise in causing phase delays of human circadian rhythms.
Am J Physiol 1997; 273 (Endocrinology and Metabolism 36):E536-42. [PMID: 9316443]
Reviews, Book Chapters, and Editorials
“Single Slide Sets to Accompany the SRS Basics of Sleep Guide (version 1.1).” Charles J. Amlaner, Orfeu M. Buxton, editors. Sleep Research Society Educational Programs Committee. 2008.
“Slide Sets to Accompany the SRS Basics of Sleep Guide.” Charles J.
Amlaner, Orfeu M. Buxton, editors.
Sleep Research Society Educational Programs Committee. 2007.
"Evidence-Based Design: The new AIA Guidelines on Noise and Privacy," Sykes, D.; Rockstroh, R.; Solet, J.; Buxton, O. Pg 47-49, Healthcare Design 09.06, Volume 6, Number 5, September 2006, www.hcdmagazine.com.
Czeisler, CA. OM Buxton, and SB Khalsa. The human circadian timing system and sleep-wake regulation. In, Principles and Practices of Sleep Medicine. M Kryger, T Roth, W Dement eds., 2005.
O'Connor PJ, SD Youngstedt, OM Buxton, and MD Breus. FIMS position statement on air travel and performance in sports. Fèdèration Internationale de Mèdecine du Sport (FIMS) Position Statement #16, 2004, pp-1-12. Available at URL: http://www.fims.org/files/311417173/PS16%20Air%20travel%20March%202004.pdf.
Shawn D. Youngstedt, Orfeu M. Buxton. Jet Lag and Athletic Performance.
Amer J Sports Med. 2003;5:219-226.
Orfeu M. Buxton and Stephen Gasior. You've got the data! Now advocate for change! Science NextWave. April 2002. http://nextwave.sciencemag.org/cgi/content/full/2002/04/16/2
Orfeu M. Buxton, Karine Spiegel, and Eve Van Cauter. Modulation of endocrine function and metabolism by sleep and sleep loss. In: T. Lee-Chiong, M. Carskadon, M. Sateia, vol. eds., Sleep Medicine 2002; 59-69.
Orfeu M. Buxton and Stephen Gasior. Surveying Postdocs: A tale from the trenches.
Science NextWave. January 2002. http://nextwave.sciencemag.org/cgi/content/full/2002/01/03/5.
Eve Van Cauter and Orfeu M. Buxton. Circadian Modulation of Endocrine Secretion. In: J. Takahashi, F.W. Turek, R.Y. Moore, vol. eds., Handbook of Neurophysiology, 2001; 685-714.
Joaquin Recio, J.M. Míguez, Orfeu M. Buxton, Etienne Challet. Synchronizing circadian rhythms in early infancy.
Medical Hypotheses. 1997 Sep;49(3):229-34. [PMID: 9293467]
Orfeu M. Buxton, Mireille L'Hermite-Balériaux, Ulrich Hirschfeld, and Eve Van Cauter. Acute and delayed effects of exercise on human melatonin secretion.
J Biol Rhythms. 1997 Dec;12(6):568-74. [PMID: 9406031]
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