Division of Sleep Medicine @ Harvard Medical School
Faculty Profile
Christopher Paul Landrigan, MD, MPH
Assistant Professor of Pediatrics and Medicine, Harvard Medical School
Associate Physician, Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital
Administrative Title(s)
Research and Fellowship Director, Inpatient Pediatrics Service, Department of Medicine, Children's Hospital
Address
Division of Sleep Medicine, 4th Floor221 Longwood Avenue
Boston, MA 02115
USA
Inter-office Mail Address
BWH Division of Sleep Medicine4th Floor
221 Longwood Avenue
Phone 617-525-7310
Email clandrigan@rics.bwh.harvard.edu
Society Memberships
Sleep Research SocietyAmerican Academy of Pediatrics
Ambulatory Pediatrics Association
Society of Hospital Medicine
Massachusetts Medical Society
Research Unit(s)
Division of Seep Medicine, Brigham and Women's Hospital
Harvard Work Hours, Health, and Safety Group
Children's Hospital Inpatient Pediatrics Service, Division of General Pediatrics, Children's Hospital Boston
Harvard Work Hours, Health, and Safety Group
Children's Hospital Inpatient Pediatrics Service, Division of General Pediatrics, Children's Hospital Boston
Research Interests
Since 1998, I have been studying the quality of the healthcare system (particularly in the inpatient setting) and patient safety. Over the past five years, I have developed a particular interest in the effects of provider sleep deprivation on patient and provider study. The Harvard Work Hours, Health, and Safety Study has consequently been conducting a series of studies to quantify the relationships between provider sleep loss and safety. We found in a randomized trial conducted at BWH that interns working traditional 30 hour shifts on a regular basis made 36% more serious medical errors, and more than five times as many serious diagnostic errors, as those whose scheduled work was limited to 16 consecutive hours (NEJM, 2004). A related nationwide study led by Laura Barger, Ph.D. found that interns driving home after working shifts >24 hours had more than twice the odds of crashing their cars (NEJM, 2005). Currently, we are engaged in ongoing studies and policy efforts to implement safer work hours for physicians, and to study the effects of long work hours in other occupational groups.
Trainees
Amy Fahrenkopf, MD, MPH 2004-Present; Patrick Conway, MD 2004-Present
Josna Adusumilli, MD
Josna Adusumilli, MD
Mentor(s)
Research Funding
1998-2000 AHCPR, Fellow
Institutional - Primary Care Research
1999-2000 Harvard Risk Management Foundation, Co-Investigator
Pediatric Medication Errors and Adverse Drug Events
1999-2000 Harvard Pilgrim Health Care Foundation, Co-PI
Impact of an Inpatient Service led by Pediatric Hospitalists
2000-2003 National PatientSafety Foundation, Co-Investigator
Serious Pediatric Medication Errors: Evaluation and Prevention Strategies
2001-2005 AHRQ/NIOSH (R01), Project Leader
Impact of Fatigue on ICU Patient and Resident Safety
2002-2003 Medimmune, Inc., PI
Bronchiolitis: Preventable Hospital Costs and Adverse Events
2002-2007 AHRQ (K08), PI
Effects of Sleep Loss and Night Work on Patient Safety
2003-2004 Harvard Risk Management Foundation, Mentor, Co-Investigator
Communication during Post-operative Patient Hand Off Events in the Pediatric Intensive Care Unit
2003-2004 Lovejoy Resident Research Fund, Children’s Hospital, Mentor, Co-Investigator
Housestaff Burnout and Depression and its Effects on Patient Safety
2003-2004 Lovejoy Resident Research Fund, Children's Hospital, Mentor, Co-Investigator
Hospitalist Management of Common Pediatric Illnesses: Predictors of Variability
2003-2004 Harvard Risk Management Foundation, Co-PI
Implementation of a Pediatric Intermediate Care Unit:Effects on Patient Safety
2004-2005 Lovejoy Resident Research Fund, Children's Hospital, Mentor, Co-Investigator
A Randomized Trial to Teach Procedural Skills to Pediatric Residents
2004-2005 Thrasher Foundation, Co-Investigator
Bronchiolitis in the ED: Low-risk Discharges and High-risk Admissions
2004-2006 National Institute of Justice (NIJ), Co-Investigator
Testing the Effectiveness of a Comprehensive Fatigue Management Program for the Boston Police
2004-2007 CDC (R01), Co-Investigator
Effectiveness of a Sleep Disorders Treatment Program to Improve Police Officer Safety
2005-2008 AHRQ (U18), PI
Implementing Reduced Work Hours for All ICU House Staff to Improve Patient Safety
2007-2008 DURIP (Department of Defense University Research Instrmnt. Program – Air Force Office of Scientific Research), Co-PI
Translating the science of alertness and performance from laboratory to field: Using state-of-the-art monitoring, imaging, and performance enhancement technologies to improve the alertness and safety of the military and civilian workforce
2007-2010 CDC (R01), Co-Investigator
Evaluation of the potential for translation to practice of a sleep disorders management program for police
Institutional - Primary Care Research
1999-2000 Harvard Risk Management Foundation, Co-Investigator
Pediatric Medication Errors and Adverse Drug Events
1999-2000 Harvard Pilgrim Health Care Foundation, Co-PI
Impact of an Inpatient Service led by Pediatric Hospitalists
2000-2003 National PatientSafety Foundation, Co-Investigator
Serious Pediatric Medication Errors: Evaluation and Prevention Strategies
2001-2005 AHRQ/NIOSH (R01), Project Leader
Impact of Fatigue on ICU Patient and Resident Safety
2002-2003 Medimmune, Inc., PI
Bronchiolitis: Preventable Hospital Costs and Adverse Events
2002-2007 AHRQ (K08), PI
Effects of Sleep Loss and Night Work on Patient Safety
2003-2004 Harvard Risk Management Foundation, Mentor, Co-Investigator
Communication during Post-operative Patient Hand Off Events in the Pediatric Intensive Care Unit
2003-2004 Lovejoy Resident Research Fund, Children’s Hospital, Mentor, Co-Investigator
Housestaff Burnout and Depression and its Effects on Patient Safety
2003-2004 Lovejoy Resident Research Fund, Children's Hospital, Mentor, Co-Investigator
Hospitalist Management of Common Pediatric Illnesses: Predictors of Variability
2003-2004 Harvard Risk Management Foundation, Co-PI
Implementation of a Pediatric Intermediate Care Unit:Effects on Patient Safety
2004-2005 Lovejoy Resident Research Fund, Children's Hospital, Mentor, Co-Investigator
A Randomized Trial to Teach Procedural Skills to Pediatric Residents
2004-2005 Thrasher Foundation, Co-Investigator
Bronchiolitis in the ED: Low-risk Discharges and High-risk Admissions
2004-2006 National Institute of Justice (NIJ), Co-Investigator
Testing the Effectiveness of a Comprehensive Fatigue Management Program for the Boston Police
2004-2007 CDC (R01), Co-Investigator
Effectiveness of a Sleep Disorders Treatment Program to Improve Police Officer Safety
2005-2008 AHRQ (U18), PI
Implementing Reduced Work Hours for All ICU House Staff to Improve Patient Safety
2007-2008 DURIP (Department of Defense University Research Instrmnt. Program – Air Force Office of Scientific Research), Co-PI
Translating the science of alertness and performance from laboratory to field: Using state-of-the-art monitoring, imaging, and performance enhancement technologies to improve the alertness and safety of the military and civilian workforce
2007-2010 CDC (R01), Co-Investigator
Evaluation of the potential for translation to practice of a sleep disorders management program for police
Selected Publications
Walsh KE, Landrigan CP, Adams WG, Vinci RJ, Chessare JB, Cooper MR, Hebert PM, Schainker EG, Bauchner H. Effect of Computer Order Entry on Prevention of Serious Medication Errors in Hospitalized Children.
Pediatrics, in press.
Landrigan CP, Fahrenkopf AM, Lewin D, Sharek PJ, Barger LK, Eisner M, Edwards S, Chiang VW, Wiedermann BL, Sectish TC. Effects of the Accreditation Council for Graduate Medical Education Duty Hour Limits on Sleep, Work Hours, and Safety.
Pediatrics, in press.
Fahrenkopf AM, Sectish TC, Barger LK, Sharek PJ, Lewin D, Chiang VW, Edwards S, Wiedermann BL, Landrigan CP. Rates of Medication Errors Among Depressed and Burned Out Residents: A Prospective Cohort Study.
BMJ, in press.
Gaies MG, Landrigan CP, Hafler JP, Sandora TJ. Assessing Procedural Skills Training in Pediatric Residency Programs.
Pediatrics. 2007 Oct;120(4):715-22. [PMID: 17908757]
Srivastava R, Landrigan CP, Ross-Degnan R, Soumerai SB, Homer DJ, Goldmann DA, Muret-Wagstaff S. Impact of a Hospitalist System on Length of Stay and Cost for Children with Common Conditions.
Pediatrics. 2007 Aug;120(2):267-74. [PMID: 17671051]
Walsh KE, Adams WG, Bauchner H, Vinci RJ, Chessare JB, Cooper MR, Hebert PM, Schainker EG, Landrigan CP. Medication Errors Related to Computer Order Entry in Children.
Pediatrics. 2006 Nov;118(5):1872-9. [PMID: 17079557]
Conway PH, Edwards S, Stucky ER, Chiang VW, Ottolini MC, Landrigan CP. Variations in management of common inpatient pediatric illnesses: hospitalists and community pediatricians.
Pediatrics. 2006 Aug;118(2):441-7. [PMID: 16882793]
Lockley SW, Landrigan CP, Barger LK, Czeisler CA. When Policy Meets Physiology: The Challenge of Reducing Resident Work Hours.
Clin Orthop Relat Res. 2006 Aug;449:116-27. [PMID: 16770285]
Landrigan CP, Barger LK, Cade BE, Ayas NT, Czeisler CA. Interns' compliance with accreditation council for graduate medical education work-hour limits.
JAMA. 2006 Sep 6;296(9):1063-70. [PMID: 16954485]
Landrigan CP, Conway P, Edwards S, Srivastava R. Pediatric Hospitalists: A Systematic Review of the Literature.
Pediatrics. 2006 May;117(5):1736-44 [PMID: 16651332]
Lye PS, Rauch D, Ottolini M, Landrigan CP, Chiang V, Srivastava R, Muret-Wagstaff S, Ludwig S. Pediatric Hospitalists: Report of a Leadership Conference.
Pediatrics. 2006 Apr;117(4):1122-30. [PMID: 16585306]
Rothschild JM, Hurley AC, Landrigan CP, Cronin JW, Martell-Waldrop K, Foskett C, Burdick E, Czeisler CA, Bates DW. Recovery from Medical Errors: The Critical Care Nursing Safety Net. Joint Commission Journal on Quality and Patient Safety. 2006 Feb;32(2):63-72. [PMID: 16568919]
McBride SA, Chiang VW, Goldmann DA, Landrigan CP. Preventable adverse events in infants hospitalized with bronchiolitis.
Pediatrics. 2005 Sep;116(3):603-8. [PMID: 16140699]
Rothschild JM, Landrigan CP, Cronin JW, Kaushal R, Lockley SE, Burdick E, Stone PH, Lilly CM, Katz JT, Czeisler CA, Bates DW. The Critical Care Safety Study: The Incidence and Nature of Adverse Events and Near-Misses in Intensive Care.
Crit Care Med. 2005 Aug;33(8):1694-700. [PMID: 16096443]
Lockley SW, Cronin JW, Evans EE, Cade BE, Lee CJ, Landrigan CP, Rothschild JM, Katz JT, Lilly CM, Stone PH, Aeschbach D, Czeisler CA. Effect of Reducing Interns' Weekly Work Hours on Sleep and Attentional Failures.
New Engl J Med. 2004 Oct 28;351(18):1829-37. [PMID: 15509816]
Landrigan CP, Rothschild JM, Cronin JW, Kaushal R, Burdick E, Katz JT, Lilly CM, Stone PH, Lockley SW, Bates DW, Czeisler CA. Effect of Reducing Interns' Work Hours on Serious Medical Errors in Intensive Care Units.
New Engl J Med. 2004 Oct 28;351(18):1838-48. [PMID: 15509817]
Willson DF, Landrigan CP, Horn SD, Smout RJ. Complications in Infants Hospitalized for Bronchiolitis or Respiratory Syncytial Virus Pneumonia.
J Pediatr. 2003 Nov;143(5 Suppl):S142-9. [PMID: 14615713]
Landrigan C. To LP or not LP: Effects of Overwork and Communication Failures on Patient Safety.
AHRQ Web M&M [serial online]. October 2003. Accessed November 13, 2003.
Fortescue EB, Kaushal R, Landrigan CP, McKenna KJ, Clapp MD, Federico F, Goldmann DA, Bates DW. Prioritizing Strategies for Preventing Medication Errors and Adverse Drug Events in Pediatric Inpatients.
Pediatrics. 2003 Apr;111(4 Pt 1):722-9. [PMID: 12671103]
Olsen SJ, Bleasdale SC, Magnano AR, Landrigan C, Holland BH, Tauxe RV, Mintz ED, Luby S. Outbreaks of Typhoid Fever in the United States, 1960-1999.
Epidemiology and Infection. 2003 Feb;130(1):13-21. [PMID: 12613741]
Bunyavanich S, Landrigan CP, McMichael AJ, Epstein PR. The Impact of Climate Change on Child Health.
Ambulatory Pediatrics. 2003 Jan-Feb;3(1):44-52. [PMID: 12540254]
Kaushal R, Landrigan CP, Bates DW. Improving Patient Safety in Massachusetts.
In: Moore RT, editor. Massachusetts Memos to the Governor. Bloomington, Indiana; 2003. p. 98-113.
Landrigan CP, Srivastava R, Muret-Wagstaff S, Soumerai SB, Ross-Degnan D, Graef JW, Homer CJ, Goldmann DA. Impact of a Health Maintenance Organization Hospitalist System in Academic Pediatrics.
Pediatrics. 2002 Oct;110(4):720-8. [PMID: 12359785]
Landrigan CP, Muret-Wagstaff S, Chiang VW, Nigrin DJ, Goldmann DA, Finkelstein JA. Effect of a Pediatric Hospitalist System on Housestaff Education and Experience.
Archives of Pediatrics and Adolescent Medicine. 2002 Sep;156(9):877-83. [PMID: 12197794]
Landrigan C, Srivastava R, Muret-Wagstaff S, Homer CJ, Goldmann DA. Pediatric Hospitalists: What do we know, and where do we go from here?
Ambulatory Pediatrics. 2001 Nov-Dec;1(6):340-5. [PMID: 11888426]
Srivastava R, Landrigan C, Gidwani P, Harary O, Muret-Wagstaff S, Homer CJ. Pediatric Hospitalists in Canada and the United States: A Survey of Pediatric Academic Department Chairs.
Ambulatory Pediatrics. 2001 Nov-Dec;1(6):338-9. [PMID: 11888425]
Kaushal R, Bates DW, Landrigan C, McKenna KJ, Clapp MD, Federico F, Goldmann DA. Medication Errors and Adverse Drug Events in Pediatric Inpatients.
JAMA. 2001 Apr 25;285(16):2114-20. [PMID: 1131110]
Other articles, editorials, letters
Landrigan CP, Czeisler CA, Barger LK, Ayas NT, Rothschild JM, Lockley SW. Reducing Fatigue-Related Errors and Injuries in Health Care: Effective Implementation of Work-Hour Limits and Systemic Improvements.
Joint Comm J Qual Patient Saf. 2007 Nov;33(11 Suppl):19-29. [PMID: 18173163]
Lockley SW, Barger LK, Ayas NT, Rothschild JM, Czeisler CA, Landrigan CP. Effects of Health Care Provider Work Hours and Sleep Deprivation on Safety and Performance.
Joint Comm J Qual Patient Saf. 2007 Nov;33(11 Suppl):7-18. [PMID: 18173162]
Landrigan CP, Czeisler CA. Drowsy Driving in Massachusetts: From Science to Policy. May 22, 2007. Available at http://www.sleepresearchsociety.org/LegislativeProcess.aspx. Accessed May 22, 2007.
Landrigan CP, Czeisler CA. Development of Safe Resident Work Hours Legislation. May 22, 2007. Available at http://www.sleepresearchsociety.org/ResidentWork.aspx. Accessed May 22, 2007.
Landrigan CP. The Handoff: A Critical Point of Vulnerability.
Forum (CRICO/Risk Management Foundation). 2007;25:6-7.
Lockley SW, Landrigan CP, Barger LK, Czeisler CA. When Policy Meets Physiology: The Challenge of Reducing Resident Work Hours.
Clinical Orthopaedics & Related Research. 2006 Aug;449:116-27. [PMID: 16770285]
Landrigan CP. New Zealand Junior Doctors - An Analysis of Current Scheduling Practices and Recommendations for the Future. June 12, 2006. Available at http://www.rcplondon.ac.uk/news/EU/ewtd_nz-jnr-doc.pdf. Accessed October 20, 2006.
Lilly CM, Landrigan CP. A Shift for the Better.
Chest. 2005 Dec;128(6):3787-8. [PMID: 16354844]
Landrigan CP. Effects of 24- to 30-hour Work Shifts on the Safety of Physicians and Patients. Massachusetts Hospital Association Workforce Summit - Keeping Patients Safe: Transforming the Work Environment. November 16th, 2005.
Landrigan CP. Sliding Down the Bell Curve: Effects of 24-hour Work Shifts on Physicians’ Cognition and Performance. Sleep. 2005 Nov 1;28(11):1351-3. [PMID: 16335321]
Landrigan CP, Lockley SE, Czeisler CA. Effect of intern's consecutive work hours on safety, medical education and professionalism [letter].
Critical Care. 2005 Oct 5;9(5):528-30; author reply 528-30. Epub 2005 May 24. [PMID: 16277743]
Landrigan CP. The Safety of Inpatient Pediatrics: Preventing Medical Errors and Injuries Among Hospitalized Children.
Pediatric Clinics of North America. 2005 Aug;52(4):979-93, vii. [PMID: 16009253]
Braund WE, Corden TE, Foley ME, Korona KM, Landrigan CP, Lucey CT, Mobley-Smith MA, Tomlinson D. A Proposal to Develop an Evidence-Based Guide to Workplace Preventive Services.
Society of Primary Care Policy Fellows. June 2005. Available at http://www.primarycaresociety.org/2005a.htm. Accessed March 20, 2007.
Landrigan CP, Czeisler CA. Questions and Answers with the Authors: Effect of Eliminating Extended Work Shifts and Reducing Weekly Work Hours on Serious Medical Errors in Intensive Care Units.
The Next Generation [serial online]. 2004.
Landrigan C. To LP or not LP: Effects of Overwork and Communication Failures on Patient Safety.
AHRQ Web M&M [serial online]. October 2003. Available at http://webmm.ahrq.gov/case.aspx?caseID=34. Accessed March 20, 2007.
Landrigan CP, Muret-Wagstaff S, Chiang VW, Nigrin DJ, Goldmann DA, Finkelstein JA. Senior Resident Autonomy in a Pediatric Hospitalist System [letter].
Archives of Pediatrics and Adolescent Medicine. 2003 Feb;157(2):206-7. [PMID: 12580695]
Landrigan C. Development of the Pediatric Research in Inpatient Settings (PRIS) Network. AAP Section on Hospital Care News. 2003;1:4.
Landrigan C. Pediatric Research in Inpatient Settings (PRIS) Network.
The Hospitalist. 2002;6(4):43.
Landrigan C, Srivastava R, Muret-Wagstaff S, Homer CJ, Goldmann DA. Pediatric Hospitalists: What do we know, and where do we go from here?
Ambulatory Pediatrics. 2001 Nov-Dec;1(6):340-5. [PMID: 11888426]
Landrigan C. Preventable Deaths and Injuries during Magnetic Resonance Imaging [letter]. New Engl J Med. 2001 Sep 27;345(13):1000-1. [PMID: 11575283]
Textbook chapters
Fahrenkopf AM, Landrigan CP. "Serious Medical Errors in Intensive Care."
In The year in anaesthesia and critical care, volume 2, ed. Hunter J, Cook T, Priebe H-J, and Struys M. Oxford, UK: Clinical Publishing Services. In press.
McBride SA, Landrigan CP. 2007. "Clinical research in the pediatric inpatient setting": Guidelines for getting started. In Comprehensive pediatric hospital medicine, ed. Zaoutis L and Chiang VW. PA: Elsevier Publishing.
Landrigan CP. 2007. "Pediatric hospital medicine": Future directions.
In Comprehensive pediatric hospital medicine, ed. Zaoutis L and Chiang VW. PA: Elsevier Publishing.
Landrigan CP, Friedman J. 2007. Patient Safety and Medical Errors in Pediatric Hospitals.
In Comprehensive pediatric hospital medicine, ed. Zaoutis L and Chiang VW. PA: Elsevier Publishing.
Kaushal R, Landrigan CP, Bates DW. 2003. Improving Patient Safety in Massachusetts.
In Massachusetts memos to the governor, ed. Moore RT, 98-113. Bloomington, Indiana. {Peer-reviewed chapter that provides original policy recommendations to the governor of Massachusetts on improving patient safety}
Non-print publications
Landrigan CP. Effects of Traditional 24-39 Hours Shifts on Patient & Resident Safety: The Case for a 16-Hour Limit. DVD Produced by Committee for Interns and Residents. CIR/SEIU 2006.
Pediatrics, in press.
Landrigan CP, Fahrenkopf AM, Lewin D, Sharek PJ, Barger LK, Eisner M, Edwards S, Chiang VW, Wiedermann BL, Sectish TC. Effects of the Accreditation Council for Graduate Medical Education Duty Hour Limits on Sleep, Work Hours, and Safety.
Pediatrics, in press.
Fahrenkopf AM, Sectish TC, Barger LK, Sharek PJ, Lewin D, Chiang VW, Edwards S, Wiedermann BL, Landrigan CP. Rates of Medication Errors Among Depressed and Burned Out Residents: A Prospective Cohort Study.
BMJ, in press.
Gaies MG, Landrigan CP, Hafler JP, Sandora TJ. Assessing Procedural Skills Training in Pediatric Residency Programs.
Pediatrics. 2007 Oct;120(4):715-22. [PMID: 17908757]
Srivastava R, Landrigan CP, Ross-Degnan R, Soumerai SB, Homer DJ, Goldmann DA, Muret-Wagstaff S. Impact of a Hospitalist System on Length of Stay and Cost for Children with Common Conditions.
Pediatrics. 2007 Aug;120(2):267-74. [PMID: 17671051]
Walsh KE, Adams WG, Bauchner H, Vinci RJ, Chessare JB, Cooper MR, Hebert PM, Schainker EG, Landrigan CP. Medication Errors Related to Computer Order Entry in Children.
Pediatrics. 2006 Nov;118(5):1872-9. [PMID: 17079557]
Conway PH, Edwards S, Stucky ER, Chiang VW, Ottolini MC, Landrigan CP. Variations in management of common inpatient pediatric illnesses: hospitalists and community pediatricians.
Pediatrics. 2006 Aug;118(2):441-7. [PMID: 16882793]
Lockley SW, Landrigan CP, Barger LK, Czeisler CA. When Policy Meets Physiology: The Challenge of Reducing Resident Work Hours.
Clin Orthop Relat Res. 2006 Aug;449:116-27. [PMID: 16770285]
Landrigan CP, Barger LK, Cade BE, Ayas NT, Czeisler CA. Interns' compliance with accreditation council for graduate medical education work-hour limits.
JAMA. 2006 Sep 6;296(9):1063-70. [PMID: 16954485]
Landrigan CP, Conway P, Edwards S, Srivastava R. Pediatric Hospitalists: A Systematic Review of the Literature.
Pediatrics. 2006 May;117(5):1736-44 [PMID: 16651332]
Lye PS, Rauch D, Ottolini M, Landrigan CP, Chiang V, Srivastava R, Muret-Wagstaff S, Ludwig S. Pediatric Hospitalists: Report of a Leadership Conference.
Pediatrics. 2006 Apr;117(4):1122-30. [PMID: 16585306]
Rothschild JM, Hurley AC, Landrigan CP, Cronin JW, Martell-Waldrop K, Foskett C, Burdick E, Czeisler CA, Bates DW. Recovery from Medical Errors: The Critical Care Nursing Safety Net. Joint Commission Journal on Quality and Patient Safety. 2006 Feb;32(2):63-72. [PMID: 16568919]
McBride SA, Chiang VW, Goldmann DA, Landrigan CP. Preventable adverse events in infants hospitalized with bronchiolitis.
Pediatrics. 2005 Sep;116(3):603-8. [PMID: 16140699]
Rothschild JM, Landrigan CP, Cronin JW, Kaushal R, Lockley SE, Burdick E, Stone PH, Lilly CM, Katz JT, Czeisler CA, Bates DW. The Critical Care Safety Study: The Incidence and Nature of Adverse Events and Near-Misses in Intensive Care.
Crit Care Med. 2005 Aug;33(8):1694-700. [PMID: 16096443]
Lockley SW, Cronin JW, Evans EE, Cade BE, Lee CJ, Landrigan CP, Rothschild JM, Katz JT, Lilly CM, Stone PH, Aeschbach D, Czeisler CA. Effect of Reducing Interns' Weekly Work Hours on Sleep and Attentional Failures.
New Engl J Med. 2004 Oct 28;351(18):1829-37. [PMID: 15509816]
Landrigan CP, Rothschild JM, Cronin JW, Kaushal R, Burdick E, Katz JT, Lilly CM, Stone PH, Lockley SW, Bates DW, Czeisler CA. Effect of Reducing Interns' Work Hours on Serious Medical Errors in Intensive Care Units.
New Engl J Med. 2004 Oct 28;351(18):1838-48. [PMID: 15509817]
Willson DF, Landrigan CP, Horn SD, Smout RJ. Complications in Infants Hospitalized for Bronchiolitis or Respiratory Syncytial Virus Pneumonia.
J Pediatr. 2003 Nov;143(5 Suppl):S142-9. [PMID: 14615713]
Landrigan C. To LP or not LP: Effects of Overwork and Communication Failures on Patient Safety.
AHRQ Web M&M [serial online]. October 2003. Accessed November 13, 2003.
Fortescue EB, Kaushal R, Landrigan CP, McKenna KJ, Clapp MD, Federico F, Goldmann DA, Bates DW. Prioritizing Strategies for Preventing Medication Errors and Adverse Drug Events in Pediatric Inpatients.
Pediatrics. 2003 Apr;111(4 Pt 1):722-9. [PMID: 12671103]
Olsen SJ, Bleasdale SC, Magnano AR, Landrigan C, Holland BH, Tauxe RV, Mintz ED, Luby S. Outbreaks of Typhoid Fever in the United States, 1960-1999.
Epidemiology and Infection. 2003 Feb;130(1):13-21. [PMID: 12613741]
Bunyavanich S, Landrigan CP, McMichael AJ, Epstein PR. The Impact of Climate Change on Child Health.
Ambulatory Pediatrics. 2003 Jan-Feb;3(1):44-52. [PMID: 12540254]
Kaushal R, Landrigan CP, Bates DW. Improving Patient Safety in Massachusetts.
In: Moore RT, editor. Massachusetts Memos to the Governor. Bloomington, Indiana; 2003. p. 98-113.
Landrigan CP, Srivastava R, Muret-Wagstaff S, Soumerai SB, Ross-Degnan D, Graef JW, Homer CJ, Goldmann DA. Impact of a Health Maintenance Organization Hospitalist System in Academic Pediatrics.
Pediatrics. 2002 Oct;110(4):720-8. [PMID: 12359785]
Landrigan CP, Muret-Wagstaff S, Chiang VW, Nigrin DJ, Goldmann DA, Finkelstein JA. Effect of a Pediatric Hospitalist System on Housestaff Education and Experience.
Archives of Pediatrics and Adolescent Medicine. 2002 Sep;156(9):877-83. [PMID: 12197794]
Landrigan C, Srivastava R, Muret-Wagstaff S, Homer CJ, Goldmann DA. Pediatric Hospitalists: What do we know, and where do we go from here?
Ambulatory Pediatrics. 2001 Nov-Dec;1(6):340-5. [PMID: 11888426]
Srivastava R, Landrigan C, Gidwani P, Harary O, Muret-Wagstaff S, Homer CJ. Pediatric Hospitalists in Canada and the United States: A Survey of Pediatric Academic Department Chairs.
Ambulatory Pediatrics. 2001 Nov-Dec;1(6):338-9. [PMID: 11888425]
Kaushal R, Bates DW, Landrigan C, McKenna KJ, Clapp MD, Federico F, Goldmann DA. Medication Errors and Adverse Drug Events in Pediatric Inpatients.
JAMA. 2001 Apr 25;285(16):2114-20. [PMID: 1131110]
Other articles, editorials, letters
Landrigan CP, Czeisler CA, Barger LK, Ayas NT, Rothschild JM, Lockley SW. Reducing Fatigue-Related Errors and Injuries in Health Care: Effective Implementation of Work-Hour Limits and Systemic Improvements.
Joint Comm J Qual Patient Saf. 2007 Nov;33(11 Suppl):19-29. [PMID: 18173163]
Lockley SW, Barger LK, Ayas NT, Rothschild JM, Czeisler CA, Landrigan CP. Effects of Health Care Provider Work Hours and Sleep Deprivation on Safety and Performance.
Joint Comm J Qual Patient Saf. 2007 Nov;33(11 Suppl):7-18. [PMID: 18173162]
Landrigan CP, Czeisler CA. Drowsy Driving in Massachusetts: From Science to Policy. May 22, 2007. Available at http://www.sleepresearchsociety.org/LegislativeProcess.aspx. Accessed May 22, 2007.
Landrigan CP, Czeisler CA. Development of Safe Resident Work Hours Legislation. May 22, 2007. Available at http://www.sleepresearchsociety.org/ResidentWork.aspx. Accessed May 22, 2007.
Landrigan CP. The Handoff: A Critical Point of Vulnerability.
Forum (CRICO/Risk Management Foundation). 2007;25:6-7.
Lockley SW, Landrigan CP, Barger LK, Czeisler CA. When Policy Meets Physiology: The Challenge of Reducing Resident Work Hours.
Clinical Orthopaedics & Related Research. 2006 Aug;449:116-27. [PMID: 16770285]
Landrigan CP. New Zealand Junior Doctors - An Analysis of Current Scheduling Practices and Recommendations for the Future. June 12, 2006. Available at http://www.rcplondon.ac.uk/news/EU/ewtd_nz-jnr-doc.pdf. Accessed October 20, 2006.
Lilly CM, Landrigan CP. A Shift for the Better.
Chest. 2005 Dec;128(6):3787-8. [PMID: 16354844]
Landrigan CP. Effects of 24- to 30-hour Work Shifts on the Safety of Physicians and Patients. Massachusetts Hospital Association Workforce Summit - Keeping Patients Safe: Transforming the Work Environment. November 16th, 2005.
Landrigan CP. Sliding Down the Bell Curve: Effects of 24-hour Work Shifts on Physicians’ Cognition and Performance. Sleep. 2005 Nov 1;28(11):1351-3. [PMID: 16335321]
Landrigan CP, Lockley SE, Czeisler CA. Effect of intern's consecutive work hours on safety, medical education and professionalism [letter].
Critical Care. 2005 Oct 5;9(5):528-30; author reply 528-30. Epub 2005 May 24. [PMID: 16277743]
Landrigan CP. The Safety of Inpatient Pediatrics: Preventing Medical Errors and Injuries Among Hospitalized Children.
Pediatric Clinics of North America. 2005 Aug;52(4):979-93, vii. [PMID: 16009253]
Braund WE, Corden TE, Foley ME, Korona KM, Landrigan CP, Lucey CT, Mobley-Smith MA, Tomlinson D. A Proposal to Develop an Evidence-Based Guide to Workplace Preventive Services.
Society of Primary Care Policy Fellows. June 2005. Available at http://www.primarycaresociety.org/2005a.htm. Accessed March 20, 2007.
Landrigan CP, Czeisler CA. Questions and Answers with the Authors: Effect of Eliminating Extended Work Shifts and Reducing Weekly Work Hours on Serious Medical Errors in Intensive Care Units.
The Next Generation [serial online]. 2004.
Landrigan C. To LP or not LP: Effects of Overwork and Communication Failures on Patient Safety.
AHRQ Web M&M [serial online]. October 2003. Available at http://webmm.ahrq.gov/case.aspx?caseID=34. Accessed March 20, 2007.
Landrigan CP, Muret-Wagstaff S, Chiang VW, Nigrin DJ, Goldmann DA, Finkelstein JA. Senior Resident Autonomy in a Pediatric Hospitalist System [letter].
Archives of Pediatrics and Adolescent Medicine. 2003 Feb;157(2):206-7. [PMID: 12580695]
Landrigan C. Development of the Pediatric Research in Inpatient Settings (PRIS) Network. AAP Section on Hospital Care News. 2003;1:4.
Landrigan C. Pediatric Research in Inpatient Settings (PRIS) Network.
The Hospitalist. 2002;6(4):43.
Landrigan C, Srivastava R, Muret-Wagstaff S, Homer CJ, Goldmann DA. Pediatric Hospitalists: What do we know, and where do we go from here?
Ambulatory Pediatrics. 2001 Nov-Dec;1(6):340-5. [PMID: 11888426]
Landrigan C. Preventable Deaths and Injuries during Magnetic Resonance Imaging [letter]. New Engl J Med. 2001 Sep 27;345(13):1000-1. [PMID: 11575283]
Textbook chapters
Fahrenkopf AM, Landrigan CP. "Serious Medical Errors in Intensive Care."
In The year in anaesthesia and critical care, volume 2, ed. Hunter J, Cook T, Priebe H-J, and Struys M. Oxford, UK: Clinical Publishing Services. In press.
McBride SA, Landrigan CP. 2007. "Clinical research in the pediatric inpatient setting": Guidelines for getting started. In Comprehensive pediatric hospital medicine, ed. Zaoutis L and Chiang VW. PA: Elsevier Publishing.
Landrigan CP. 2007. "Pediatric hospital medicine": Future directions.
In Comprehensive pediatric hospital medicine, ed. Zaoutis L and Chiang VW. PA: Elsevier Publishing.
Landrigan CP, Friedman J. 2007. Patient Safety and Medical Errors in Pediatric Hospitals.
In Comprehensive pediatric hospital medicine, ed. Zaoutis L and Chiang VW. PA: Elsevier Publishing.
Kaushal R, Landrigan CP, Bates DW. 2003. Improving Patient Safety in Massachusetts.
In Massachusetts memos to the governor, ed. Moore RT, 98-113. Bloomington, Indiana. {Peer-reviewed chapter that provides original policy recommendations to the governor of Massachusetts on improving patient safety}
Non-print publications
Landrigan CP. Effects of Traditional 24-39 Hours Shifts on Patient & Resident Safety: The Case for a 16-Hour Limit. DVD Produced by Committee for Interns and Residents. CIR/SEIU 2006.
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